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Note 10 - Property, Plant and Equipment (Tables)
12 Months Ended
Dec. 31, 2022
Notes Tables  
Property, Plant and Equipment [Table Text Block]
  

December 31,
2022

  

December 31,
2021

 

Computers, software and office equipment

 $463,292  $517,488 

Laboratory equipment

  3,559,362   3,456,091 

Leasehold improvements

  535,527   428,596 

Manufacturing tooling

  121,120   121,120 

Demo equipment

  31,554   56,614 

Total

  4,710,855   4,579,909 

Less: Accumulated depreciation

  2,877,600   2,068,338 

Total fixed assets, net

 $1,833,255  $2,511,571