Note 13 - Segments - Segments (Details) - USD ($)	3 Months Ended	9 Months Ended		12 Months Ended
	Dec. 31, 2020	Sep. 30, 2021	Sep. 30, 2020	Dec. 31, 2021	Dec. 31, 2020
Revenue				$ 1,420,680	$ 1,252,272
Depreciation and Amortization				(1,340,301)	(1,024,848)
Impairment	$ (9,879,498)	$ (2,813,792)	$ (2,997,000)	(2,813,792)	(12,876,498)
Impairment expense – intangibles				(2,893,548)	0
Impairment expense – acquired software				(1,249,727)	0
Net loss				(19,657,174)	(25,884,397)
Assets	13,060,436			43,771,271	13,060,436
Impairment expense					(12,876,498)
Net loss				(19,657,174)	(25,884,397)
Corporate, Non-Segment [Member]
Revenue				4,119	0
Depreciation and Amortization				(16,319)	(41,362)
Net loss				(7,089,286)	(8,968,648)
Assets	211,510			28,536,489	211,510
Impairment expense					0
Net loss				(7,089,286)	(8,968,648)
Skyline [Member] | Operating Segments [Member]
Revenue				1,169,811	1,185,214
Depreciation and Amortization				(30,002)	(38,310)
Net loss				(520,822)	(1,132,251)
Assets	1,191,439			906,977	1,191,439
Impairment expense					0
Net loss				(520,822)	(1,132,251)
Helomics Segment [Member] | Operating Segments [Member]
Revenue				13,367	64,188
Depreciation and Amortization				(886,642)	(761,105)
Impairment				(2,813,792)
Impairment expense – intangibles				(2,893,548)
Impairment expense – acquired software				(1,249,727)
Net loss				(11,326,948)	(15,112,131)
Assets	9,773,902			1,802,792	9,773,902
Impairment expense					(12,876,498)
Net loss				(11,326,948)	(15,112,131)
Soluble [Member] | Operating Segments [Member]
Revenue				233,293	2,870
Depreciation and Amortization				(366,713)	(184,071)
Net loss				(1,251,564)	(671,367)
Assets	$ 1,883,585			1,742,445	1,883,585
Impairment expense					0
Net loss				(1,251,564)	$ (671,367)
zPREDICTA [Member] | Operating Segments [Member]
Revenue				90
Depreciation and Amortization				(40,625)
Net loss				531,446
Assets				10,782,568
Net loss				$ 531,446