Note 11 - Leases (Details Textual)	12 Months Ended
	Dec. 31, 2021 USD ($) ft²	Dec. 31, 2020 USD ($)
Operating Lease, Expense | $	$ 595,669	$ 565,581
Corporate Office, Minnesota [Member]
Lessee, Operating Lease, Term of Contract (Year)	3 years
Area of Real Estate Property (Square Foot)	5,773
Corporate Office, Minnesota, Used for Office Space [Member]
Area of Real Estate Property (Square Foot)	2,945
Corporate Office, Minnesota, Used for Manufacturing [Member]
Area of Real Estate Property (Square Foot)	2,828
Helomics' Offices [Member]
Lessee, Operating Lease, Term of Contract (Year)	3 years
Area of Real Estate Property (Square Foot)	17,417
Helomics Offices, Lease Area for Office Space [Member]
Area of Real Estate Property (Square Foot)	1,000
Helomics Offices, Lease Area for Laboratory [Member]
Area of Real Estate Property (Square Foot)	16,417
zPREDICTA Offices in San Jose California [Member]
Area of Real Estate Property (Square Foot)	1,236
Soluble Biodtech Offices in Birmingham, Alabama [Member]
Area of Real Estate Property (Square Foot)	4,314
TumorGenesis Offices In Salem Massachusetts [Member]
Area of Real Estate Property (Square Foot)	1,450
Skyline Medical Europe’s Offices Lease [Member]
Area of Real Estate Property (Square Foot)	2,000
Skyline Medical Europe's Offices Lease, Storage Space [Member]
Area of Real Estate Property (Square Foot)	750
Skyline Medical Europe's Offices Lease, Office Space [Member]
Area of Real Estate Property (Square Foot)	1,250