Note 9 - Income Taxes (Details Textual) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Income Tax Expense (Benefit), Total	$ (661,658)	$ 0
Valuation Allowance Percentage	100.00%
Unrecognized Tax Benefits, Ending Balance	$ 0
Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued, Total	0	0
Domestic Tax Authority [Member]
Operating Loss Carryforwards, Total	308,990,822	297,735,754
Deferred Tax Assets, Operating Loss Carryforwards, Subject to Expiration	259,490,005	261,455,216
Deferred Tax Assets, Operating Loss Carryforwards, Not Subject to Expiration	49,500,817	36,280,538
Operating Loss Carryforwards, Valuation Allowance, Total	62,034,750	59,913,739
State and Local Jurisdiction [Member]
Operating Loss Carryforwards, Total	227,277,399	222,290,524
Operating Loss Carryforwards, Valuation Allowance, Total	$ 23,145,374	22,191,346
Foreign Tax Authority [Member]
Operating Loss Carryforwards, Valuation Allowance, Total		$ 0