Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($)	Preferred Stock [Member] Series B Convertible Preferred Stock [Member] Registered Direct Offerings [Member]	Preferred Stock [Member] Series B Convertible Preferred Stock [Member] Private Placement [Member]	Preferred Stock [Member] Series B Convertible Preferred Stock [Member] Registered Direct Offering [Member]	Preferred Stock [Member] Series B Convertible Preferred Stock [Member] May 2020 Offering [Member]	Preferred Stock [Member] Series B Convertible Preferred Stock [Member] Bridge Notes [Member]	Preferred Stock [Member] Series B Convertible Preferred Stock [Member] Series E Preferred Stock Conversions [Member]	Preferred Stock [Member] Series B Convertible Preferred Stock [Member] Conversion of Series E Preferred Stock [Member]	Preferred Stock [Member] Series B Convertible Preferred Stock [Member] Conversion of Series D Preferred Stock to Common Stock [Member]	Preferred Stock [Member] Series B Convertible Preferred Stock [Member] Prefunded Warrants [Member]	Preferred Stock [Member] Series B Convertible Preferred Stock [Member] New Warrants From Exercise of Warrants [Member]	Preferred Stock [Member] Series B Convertible Preferred Stock [Member]	Preferred Stock [Member] Series D Convertible Preferred Stock [Member] May 2020 Offering [Member]	Preferred Stock [Member] Series D Convertible Preferred Stock [Member] Bridge Notes [Member]	Preferred Stock [Member] Series D Convertible Preferred Stock [Member] Series E Preferred Stock Conversions [Member]	Preferred Stock [Member] Series D Convertible Preferred Stock [Member] Conversion of Series E Preferred Stock [Member]	Preferred Stock [Member] Series D Convertible Preferred Stock [Member] Conversion of Series D Preferred Stock to Common Stock [Member]	Preferred Stock [Member] Series D Convertible Preferred Stock [Member] Prefunded Warrants [Member]	Preferred Stock [Member] Series D Convertible Preferred Stock [Member] New Warrants From Exercise of Warrants [Member]	Preferred Stock [Member] Series D Convertible Preferred Stock [Member]	Preferred Stock [Member] Series E Convertible Preferred Stock [Member] May 2020 Offering [Member]	Preferred Stock [Member] Series E Convertible Preferred Stock [Member] Bridge Notes [Member]	Preferred Stock [Member] Series E Convertible Preferred Stock [Member] Series E Preferred Stock Conversions [Member]	Preferred Stock [Member] Series E Convertible Preferred Stock [Member] Conversion of Series E Preferred Stock [Member]	Preferred Stock [Member] Series E Convertible Preferred Stock [Member] Conversion of Series D Preferred Stock to Common Stock [Member]	Preferred Stock [Member] Series E Convertible Preferred Stock [Member] Prefunded Warrants [Member]	Preferred Stock [Member] Series E Convertible Preferred Stock [Member] New Warrants From Exercise of Warrants [Member]	Preferred Stock [Member] Series E Convertible Preferred Stock [Member]	Common Stock [Member] Registered Direct Offerings [Member]	Common Stock [Member] Private Placement [Member]	Common Stock [Member] Registered Direct Offering [Member]	Common Stock [Member] May 2020 Offering [Member]	Common Stock [Member] Bridge Notes [Member]	Common Stock [Member] Series E Preferred Stock Conversions [Member]	Common Stock [Member] Conversion of Series E Preferred Stock [Member]	Common Stock [Member] Conversion of Series D Preferred Stock to Common Stock [Member]	Common Stock [Member] Prefunded Warrants [Member]	Common Stock [Member] New Warrants From Exercise of Warrants [Member]	Common Stock [Member]	Additional Paid-in Capital [Member] Registered Direct Offerings [Member]	Additional Paid-in Capital [Member] Private Placement [Member]	Additional Paid-in Capital [Member] Registered Direct Offering [Member]	Additional Paid-in Capital [Member] May 2020 Offering [Member]	Additional Paid-in Capital [Member] Bridge Notes [Member]	Additional Paid-in Capital [Member] Series E Preferred Stock Conversions [Member]	Additional Paid-in Capital [Member] Conversion of Series E Preferred Stock [Member]	Additional Paid-in Capital [Member] Conversion of Series D Preferred Stock to Common Stock [Member]	Additional Paid-in Capital [Member] Prefunded Warrants [Member]	Additional Paid-in Capital [Member] New Warrants From Exercise of Warrants [Member]	Additional Paid-in Capital [Member]	Retained Earnings [Member] Registered Direct Offerings [Member]	Retained Earnings [Member] Private Placement [Member]	Retained Earnings [Member] Registered Direct Offering [Member]	Retained Earnings [Member] May 2020 Offering [Member]	Retained Earnings [Member] Bridge Notes [Member]	Retained Earnings [Member] Series E Preferred Stock Conversions [Member]	Retained Earnings [Member] Conversion of Series E Preferred Stock [Member]	Retained Earnings [Member] Conversion of Series D Preferred Stock to Common Stock [Member]	Retained Earnings [Member] Prefunded Warrants [Member]	Retained Earnings [Member] New Warrants From Exercise of Warrants [Member]	Retained Earnings [Member]	Registered Direct Offerings [Member]	Private Placement [Member]	Registered Direct Offering [Member]	May 2020 Offering [Member]	Bridge Notes [Member]	Series E Preferred Stock Conversions [Member]	Conversion of Series E Preferred Stock [Member]	Conversion of Series D Preferred Stock to Common Stock [Member]	Prefunded Warrants [Member]	New Warrants From Exercise of Warrants [Member]	Total
Balance (in shares) at Dec. 31, 2019											79,246								3,500,000								258											4,056,652
Balance at Dec. 31, 2019											$ 792								$ 35,000								$ 3											$ 40,567											$ 93,653,667											$ (82,498,711)											$ 11,231,318
Shares issued pursuant to agreement with former CEO related to accrued interest (in shares)																																						50,000
Shares issued pursuant to agreement with former CEO related to accrued interest																																						$ 500											129,500																						130,000
Stock issued, conversions (in shares)																						(50)										170,000	141,191
Stock issued, conversions																						$ (1)										$ 1,700	$ 1,412										$ 265,628	$ (1,411)																					$ 267,328	$ 0
Vesting expense																																																	287,838																						287,838
Net loss																																																												(4,529,317)											(4,529,317)
Shares issued pursuant to Equity Line (in shares)																																						943,000
Shares issued pursuant to Equity Line																																						$ 9,430											1,860,469																						1,869,899
Inducement shares issued pursuant to promissory note extension (in shares)																																						30,000
Inducement shares issued pursuant to promissory note extension																																						$ 300											40,950																						41,250
Issuance of shares and prefunded warrants pursuant to March 2020 private placement (in shares)																																						260,000
Issuance of shares and prefunded warrants pursuant to March 2020 private placement																																						$ 2,600											455,223																						457,823
Inducement shares issued pursuant to 2020 convertible debt and warrants (in shares)																																						46,875
Inducement shares issued pursuant to 2020 convertible debt and warrants																																						$ 468											119,532																						120,000
Warrants issued pursuant to 2020 convertible debt																																																	116,951																						116,951
Shares issued to consultant and other (in shares)																																						155,000
Shares issued to consultant and other																																						$ 1,550											360,750																						362,300
Balance (in shares) at Mar. 31, 2020											79,246								3,500,000								208											5,852,718
Balance at Mar. 31, 2020											$ 792								$ 35,000								$ 2											$ 58,527											97,289,097											(87,028,028)											10,355,390
Balance (in shares) at Dec. 31, 2019											79,246								3,500,000								258											4,056,652
Balance at Dec. 31, 2019											$ 792								$ 35,000								$ 3											$ 40,567											93,653,667											(82,498,711)											11,231,318
Net loss																																																																							(8,106,695)
Balance (in shares) at Jun. 30, 2020											79,246								0								0											13,190,787
Balance at Jun. 30, 2020											$ 792								$ 0								$ 0											$ 131,908											102,163,864											(90,605,406)											11,691,158
Balance (in shares) at Mar. 31, 2020											79,246								3,500,000								208											5,852,718
Balance at Mar. 31, 2020											$ 792								$ 35,000								$ 2											$ 58,527											97,289,097											(87,028,028)											10,355,390
Shares issued pursuant to agreement with former CEO related to accrued interest (in shares)																																						1,533,481
Shares issued pursuant to agreement with former CEO related to accrued interest																																						$ 15,335											2,177,543																						2,192,878
Issuance of shares and warrants (in shares)																															1,396,826
Issuance of shares and warrants																															$ 13,968											$ 591,949																						$ 605,917
Exercise of warrants (in shares)																																				1,390,166	1,274,826
Exercise of warrants																																				$ 13,902	$ 12,748										$ (13,148)	$ 1,682,237																					$ 754	$ 1,694,985
Stock issued, conversions (in shares)																(3,500,000)							(208)											1,257,416	350,004
Stock issued, conversions																$ (35,000)							$ (2)											$ 12,574	$ 3,500										$ (12,572)	$ 31,500																					$ 0	$ 0
Vesting expense																																																	134,939																						134,939
Net loss																																																												(3,577,378)											(3,577,378)
Warrants issued pursuant to 2020 convertible debt																																																	62,373																						62,373
Shares issued in connection with Asset Purchase Agreement (in shares)																																						115,000
Shares issued in connection with Asset Purchase Agreement																																						$ 1,150											185,150																						186,300
Director compensation (in shares)																																						20,350
Director compensation																																						$ 204											34,796																						35,000
Balance (in shares) at Jun. 30, 2020											79,246								0								0											13,190,787
Balance at Jun. 30, 2020											$ 792								$ 0								$ 0											$ 131,908											102,163,864											(90,605,406)											11,691,158
Balance (in shares) at Dec. 31, 2020											79,246																											19,804,787
Balance at Dec. 31, 2020											$ 792																											$ 198,048											110,826,949											(108,383,108)											2,642,681
Shares issued pursuant to agreement with former CEO related to accrued interest (in shares)																																						100,401
Shares issued pursuant to agreement with former CEO related to accrued interest																																						$ 1,004											142,569																						143,573
Issuance of shares and warrants (in shares)																												13,488,098	9,043,766
Issuance of shares and warrants																												$ 134,881	$ 90,438										$ 14,877,611	$ 15,974,301																					$ 15,012,492	$ 16,064,739
Exercise of warrants (in shares)																																						5,247,059
Exercise of warrants																																						$ 52,471											4,442,799																						4,495,270
Stock issued, conversions (in shares)																																						1,107,544
Stock issued, conversions																																						$ 11,075											502,936																						514,011
Shares issued to consultant & other (in shares)																																						2,665
Shares issued to consultant & other																																						$ 27											(4,075)																						(4,048)
Vesting expense																																																	565,082																						565,082
Net loss																																																												(3,888,713)											(3,888,713)
Balance (in shares) at Mar. 31, 2021											79,246																											48,794,320
Balance at Mar. 31, 2021											$ 792																											$ 487,944											147,328,172											(112,271,821)											35,545,087
Balance (in shares) at Dec. 31, 2020											79,246																											19,804,787
Balance at Dec. 31, 2020											$ 792																											$ 198,048											110,826,949											(108,383,108)											2,642,681
Net loss																																																																							(6,462,645)
Balance (in shares) at Jun. 30, 2021											79,246																											65,335,159
Balance at Jun. 30, 2021											$ 792																											$ 653,352											167,279,695											(114,845,753)											53,088,086
Balance (in shares) at Mar. 31, 2021											79,246																											48,794,320
Balance at Mar. 31, 2021											$ 792																											$ 487,944											147,328,172											(112,271,821)											35,545,087
Shares issued pursuant to agreement with former CEO related to accrued interest (in shares)																																						400,000
Shares issued pursuant to agreement with former CEO related to accrued interest																																						$ 4,000											(4,000)																						0
Issuance of shares and warrants (in shares)																														15,520,911
Issuance of shares and warrants																														$ 155,209											$ 19,291,087																						$ 19,446,296
Shares issued to consultant & other (in shares)																																						47,424
Shares issued to consultant & other																																						$ 474											48,238																						48,802
Vesting expense																																																	33,243																						33,243
Net loss																																																												(2,573,932)											(2,573,932)
Shares issued pursuant to Equity Line (in shares)																																						572,504
Shares issued pursuant to Equity Line																																						$ 5,725											582,865																						588,590
Balance (in shares) at Jun. 30, 2021											79,246																											65,335,159
Balance at Jun. 30, 2021											$ 792																											$ 653,352											$ 167,279,695											$ (114,845,753)											$ 53,088,086