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Note 7 - Stockholders' Equity, Stock Options and Warrants (Details Textual)
1 Months Ended 3 Months Ended 4 Months Ended 6 Months Ended
Jun. 12, 2020
shares
May 27, 2020
USD ($)
shares
May 08, 2020
USD ($)
$ / shares
shares
Apr. 21, 2020
USD ($)
$ / shares
shares
Apr. 04, 2020
shares
Mar. 18, 2020
$ / shares
shares
Oct. 24, 2019
USD ($)
shares
Jun. 30, 2020
USD ($)
$ / shares
shares
May 31, 2020
shares
Mar. 18, 2020
USD ($)
$ / shares
shares
Apr. 30, 2019
shares
Jun. 30, 2020
USD ($)
$ / shares
shares
Mar. 31, 2020
USD ($)
Jun. 30, 2019
USD ($)
Mar. 31, 2019
USD ($)
Sep. 30, 2019
USD ($)
shares
Jun. 30, 2020
USD ($)
$ / shares
shares
Jun. 30, 2019
USD ($)
Jan. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
$ / shares
shares
Stock Issued During Period, Value, New Issues | $                         $ 130,000              
Debt Instrument, Face Amount | $               $ 4,694,476       $ 4,694,476         $ 4,694,476     $ 5,146,226
Common Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares               $ 0.01       $ 0.01         $ 0.01     $ 0.01
Share-based Payment Arrangement, Expense | $                       $ 134,939   $ 1,380,620     $ 422,777 $ 1,644,220    
Share-based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount | $                           $ 59,210       $ 59,210    
Share-based Payment Arrangement, Option [Member]                                        
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition (Month)                                 1 year 180 days      
Other Capitalized Property Plant and Equipment [Member]                                        
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Property, Plant, and Equipment, Total | $   $ 1,492,500                                    
Asset Purchase Agreement with InventaBiotech and Its Subsidiaries, Soluble and BioDeth [Member]                                        
Business Acquisition, Equity Interest Issued or Issuable, Number of Shares (in shares)   125,000                                    
Asset Purchase Shares Issued Shares Escrow Deposit To Be Released Upon Six Months Anniversary Of Closing (in shares)   (25,000)                                    
Asset Purchase Shares Issued, Shares Escrow Deposit To Be Released Upon Nine Months Anniversary Of Closing (in shares)   25,000                                    
Business Acquisition, Right to Reclaim, Number of Shares (in shares)   10,000                                    
Conversion of Promissory Note Into Common Stock [Member]                                        
Shares Issued, Price Per Share (in dollars per share) | $ / shares       $ 1.43                                
DrSchwartz Notes [Member]                                        
Debt Instrument, Face Amount | $       $ 2,115,000                       $ 2,115,000 $ 2,115,000
DrSchwartz Notes [Member] | Conversion of Promissory Note Into Common Stock [Member]                                        
Debt Conversion, Converted Instrument, Shares Issued (in shares)       1,533,481                                
Equity Incentive Plan [Member] | Maximum [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period (Year)                                 3 years      
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period (Year)                                 10 years      
Equity Incentive Plan [Member] | Minimum [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period (Year)                                 3 years      
Warrants issued with Private Placement [Member]                                        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)     1,396,826     1,390,166       1,390,166                    
Price of Warrant (in dollars per share) | $ / shares           $ 2.12                            
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares     $ 1.45     $ 0.001       $ 0.001                    
Warrants and Rights Outstanding, Term (Year)     5 years 182 days                                  
Shares Issued, Price Per Share (in dollars per share) | $ / shares     $ 1.575                                  
Series A Warrants [Member]                                        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)           1,650,166       1,650,166                    
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares           $ 1.88       $ 1.88                    
Warrants and Rights Outstanding, Term (Year)           5 years 182 days       5 years 182 days                    
Series B Warrants [Member]                                        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)           1,650,166       1,650,166                    
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares           $ 1.88       $ 1.88                    
Warrants and Rights Outstanding, Term (Year)           2 years       2 years                    
Prefunded Warrant [Member]                                        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)           1,390,166       1,390,166                    
Price of Warrant (in dollars per share) | $ / shares                   $ 2.12                    
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares           $ 0.0001       $ 0.0001                    
Warrant Issued in Connection With May 2020 Offering [Member]                                        
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares               $ 1.45       $ 1.45         $ 1.45      
Class of Warrant or Right Issued During Period (in shares)               1,396,826                        
June 2020 Warrant [Member]                                        
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares               $ 1.80       $ 1.80         $ 1.80      
Warrants and Rights Outstanding, Term (Year)               5 years 182 days       5 years 182 days         5 years 182 days      
Class Of Warrant Or Right, Purchase Price Per Warrant (in dollars per share) | $ / shares               $ 0.125       $ 0.125         $ 0.125      
Class of Warrant or Right, Percentage of Shares Issued Pursuant to Exercise of Existing Warrant               100.00%       100.00%         100.00%      
Proceeds from Issuance and Exercise of Warrants | $               $ 2,130,701                        
Proceeds from Issuance and Exercise of Warrants, Net | $               1,865,800                        
Equity Line Purchase Agreement [Member]                                        
Issuance or Sale of Equity, Can Be Raised | $             $ 15,000,000                          
Stock Issued During Period, Shares, New Issues (in shares)             104,651                   943,000      
Stock Issued During Period, Value, New Issues | $             $ 450,000                   $ 1,869,899      
Sale of Stock, Remaining Available Balance | $               $ 12,810,907       $ 12,810,907         $ 12,810,907      
Private Placement [Member]                                        
Stock Issued During Period, Shares, New Issues (in shares)     1,396,826             260,000                    
Stock Issued During Period, Value, New Issues | $                             $ 2,429,709          
Sale of Stock, Price Per Share (in dollars per share) | $ / shares           $ 2.121       $ 2.121                    
Proceeds from Issuance or Sale of Equity, Total | $                   $ 3,498,612                    
Proceeds from Issuance or Sale of Equity, Net of Stock Issuance Costs | $                   $ 3,127,818                    
Common Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares     $ 0.01                                  
Registered Direct Offering [Member]                                        
Proceeds from Issuance or Sale of Equity, Total | $     $ 2,200,001                                  
Proceeds from Issuance or Sale of Equity, Net of Stock Issuance Costs | $     $ 1,930,101                                  
Conversion from Series D Preferred Stock to Common Stock [Member]                                        
Conversion of Stock, Shares Converted (in shares)         3,500,000                              
Conversion of Stock, Shares Issued (in shares)         350,004                              
Conversion from Series E Preferred Stock to Common Stock [Member]                                        
Conversion of Stock, Shares Converted (in shares)                 207.7                      
Conversion of Stock, Shares Issued (in shares) 1,257,416                                      
Conversion of Stock, Shares Issued, Percentage of Outstanding Shares 11.80%               0.05686%                      
Preferred Stock, Shares Outstanding, Ending Balance (in shares) 207.7                                      
Series D Preferred Stock [Member]                                        
Preferred Stock, Shares Issued, Total (in shares)                     3,500,000                  
Convertible Preferred Stock, Conversion Rate                     10                  
Series E Convertible Preferred Stock [Member]                                        
Convertible Preferred Stock, Conversion Rate                               0.00056857        
Stock Issued During Period, Shares, Convertible Preferred Shares Issued (in shares)                               258        
Preferred Stock, Beneficial Conversion Feature | $                               $ 289,935        
Preferred Stock, Shares Outstanding, Ending Balance (in shares)               0       0         0     285