Note 11 - Subsequent Events (Details Textual)							1 Months Ended
	Jun. 13, 2020 shares	May 27, 2020 shares	May 08, 2020 USD ($) $ / shares shares	Apr. 21, 2020 USD ($) $ / shares shares	Apr. 20, 2020 USD ($)	Apr. 04, 2020 shares	Mar. 18, 2020 USD ($) $ / shares shares	Apr. 30, 2019 shares	Mar. 31, 2020 USD ($) $ / shares	Jan. 31, 2020 USD ($)	Dec. 31, 2019 USD ($) $ / shares
Debt Instrument, Face Amount | $									$ 6,425,666		$ 5,146,226
Common Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares									$ 0.01		$ 0.01
Conversion from Series E Preferred Stock to Common Stock [Member] | Forecast [Member]
Conversion of Stock, Shares Converted (in shares)	207.7
Conversion of Stock, Conversion Percentage	0.05686%
Conversion of Stock, Shares Issued, Percentage of Outstanding Shares	11.8092%
Series D Preferred Stock [Member]
Preferred Stock, Shares Issued, Total (in shares)								3,500,000
Convertible Preferred Stock, Conversion Rate								10
Warrants issued with Private Placement [Member]
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares							$ 1.88
Private Placement [Member]
Stock Issued During Period, Shares, New Issues (in shares)							260,000
Proceeds from Issuance or Sale of Equity, Total | $							$ 3,498,612
Proceeds from Issuance or Sale of Equity, Net of Stock Issuance Costs | $							$ 3,127,818
DrSchwartz Notes [Member]
Debt Instrument, Face Amount | $									$ 2,115,000	$ 2,115,000	$ 2,115,000
Debt Instrument, Interest Rate, Stated Percentage										12.00%
Short-term Debt, Total | $									$ 2,115,000
Subsequent Event [Member]
Proceeds from Paycheck Protection Program Under CARES Act | $					$ 541,867
Subsequent Event [Member] | Conversion from Series D Preferred Stock to Common Stock [Member]
Conversion of Stock, Shares Converted (in shares)						3,500,000
Conversion of Stock, Shares Issued (in shares)						350,004
Subsequent Event [Member] | Warrants issued with Private Placement [Member]
Shares Issued, Price Per Share (in dollars per share) | $ / shares			$ 1.575
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)			1,396,826
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares			$ 1.45
Warrants and Rights Outstanding, Term (Year)			5 years 182 days
Subsequent Event [Member] | Private Placement [Member]
Stock Issued During Period, Shares, New Issues (in shares)			1,396,826
Common Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares			$ 0.01
Subsequent Event [Member] | Registered Direct Offering [Member]
Proceeds from Issuance or Sale of Equity, Total | $			$ 2,200,001
Proceeds from Issuance or Sale of Equity, Net of Stock Issuance Costs | $			$ 1,930,101
Subsequent Event [Member] | Dr. Schwartz [Member]
Shares Issued, Price Per Share (in dollars per share) | $ / shares				$ 1.43
Stock Issued, Agreement, Not to be Transferred or Sold For Three Months (in shares)				766,740
Stock Issued, Agreement, Not to be Transferred or Sold for Six Months (in shares)				766,741
Subsequent Event [Member] | Dr. Schwartz [Member] | Conversion of Promissory Note Into Common Stock [Member]
Debt Conversion, Converted Instrument, Shares Issued (in shares)				1,533,481
Subsequent Event [Member] | DrSchwartz Notes [Member]
Interest Payable | $				$ 77,878
Short-term Debt, Total | $				$ 2,192,878
Acquisition from Soluble Therapeutics and BioDtech [Member] | Subsequent Event [Member]
Business Acquisition, Equity Interest Issued or Issuable, Number of Shares (in shares)		125,000