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Note 8 - Loss Per Share (Tables)
3 Months Ended
Mar. 31, 2020
Notes Tables  
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
    Three Months Ended March 31,
    2020   2019
Numerator:        
Net loss attributable to common shareholders per common share: basic and diluted calculation   $
(4,529,317
)   $
(3,293,184
)
                 
Denominator:                
Weighted average common shares outstanding-basic (1)    
4,886,328
     
1,573,152
 
Effect of diluted stock options, warrants and preferred stock (2)    
-
     
-
 
Weighted average common shares outstanding-diluted    
4,886,328
     
1,573,152
 
Loss per common share-basic and diluted   $
(0.93
)   $
(2.09
)
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
    Three Months Ended March 31,
    2020   2019
Options    
794,038
     
407,158
 
Warrants    
5,663,594
     
595,113
 
Convertible debt    
378,000
     
504,770
 
Preferred stock: series B    
7,925
     
7,925
 
Preferred stock: series D    
350,000
     
-
 
Preferred stock: series E    
691,159
     
-