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Note 13 - Subsequent Events (Details Textual) - USD ($)							1 Months Ended		2 Months Ended	3 Months Ended	12 Months Ended
Note 13 - Subsequent Events (Details Textual) - USD ($)	Mar. 19, 2020	Mar. 15, 2020	Mar. 05, 2020	Mar. 04, 2020	Mar. 02, 2020	Jul. 10, 2018	Feb. 29, 2020	Jan. 31, 2020	Apr. 06, 2020	Mar. 27, 2020	Dec. 31, 2019	Dec. 31, 2018	Mar. 07, 2020	Feb. 05, 2020
Stock Issued During Period, Value, Inducement to Equity Line											$ 450,000
Debt Instrument, Face Amount											5,146,226	$ 2,667,727
Debt Conversion, Converted Instrument, Amount											378,573
Gain (Loss) on Extinguishment of Debt, Total											$ (581,073)
Stock Issued During Period, Shares, Issued for Services						25,000
Stock Issued During Period, Shares, Extension of Notes Payable											30,000
CEO Promissory Note Exchange Agreement [Member]
Gain (Loss) on Extinguishment of Debt, Total											$ 310,000
Notes Payable [Member]
Debt Instrument, Increase for Extension	$ 300,000
Promissory Note [Member]
Debt Instrument, Face Amount											$ 680,833
Promissory Note [Member] \| Forecast [Member]
Proceeds from Short-term Debt, Total									$ 1,200,000
Subsequent Event [Member]
Stock Issued During Period, Shares, Inducement to Equity Line										943,000
Stock Issued During Period, Value, Inducement to Equity Line										$ 1,869,899
Stock Issued During Period, Shares, Extension of Notes Payable	30,000
Subsequent Event [Member] \| Private Placement [Member]
Stock Issued During Period, Shares, New Issues		260,000
Sale of Stock, Price Per Share		$ 2.12
Proceeds from Issuance or Sale of Equity, Total		$ 3,498,612
Proceeds from Issuance or Sale of Equity, Net of Stock Issuance Costs		$ 3,127,112
Subsequent Event [Member] \| Chief Executive Officer [Member]
Debt Conversion, Converted Instrument, Shares Issued								50,000
Subsequent Event [Member] \| Chief Executive Officer [Member] \| Promissory Note Exchange Agreement [Member]
Debt Conversion, Converted Instrument, Amount								$ 2,115,000
Subsequent Event [Member] \| Investor of Promissory Note [Member]
Stock Issued During Period, Shares, New Issues							46,875
Subsequent Event [Member] \| InventaBio Tech and its subsidiary Soluble [Member]
Stock Issued During Period, Shares, Purchase of Assets					125,000
Subsequent Event [Member] \| Vendor [Member]
Stock Issued During Period, Shares, Issued for Services				150,000
Subsequent Event [Member] \| Warrants Issued With Promissory Note, One [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights							94,631
Subsequent Event [Member] \| Warrants Issued With Promissory Note, Two [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights													92,700
Subsequent Event [Member] \| Warrants Issued With Promissory Note [Member]
Class of Warrant or Right, Exercise Price of Warrants or Rights														$ 2.992
Subsequent Event [Member] \| Warrants issued with Private Placement, One [Member]
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right		1
Warrants and Rights Outstanding, Term		5 years 182 days
Subsequent Event [Member] \| Warrants issued with Private Placement, Two [Member]
Class of Warrant or Right, Exercise Price of Warrants or Rights		$ 1.88
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right		1
Warrants and Rights Outstanding, Term		2 years
Subsequent Event [Member] \| Prefunded Warrant [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights		1,390,166
Class of Warrant or Right, Exercise Price of Warrants or Rights		$ 0.0001
Price of Warrant		$ 2.12
Subsequent Event [Member] \| Loans Payable [Member]
Debt Instrument, Face Amount										1,098,684
Proceeds from Short-term Debt, Total										1,020,000
Repayments of Short-term Debt, Total										$ 657,105
Subsequent Event [Member] \| Promissory Note [Member]
Debt Instrument, Face Amount														$ 1,450,000
Debt Instrument, Interest Rate, Stated Percentage														8.00%
Subsequent Event [Member] \| Promissory Note [Member] \| Chief Executive Officer [Member]
Debt Instrument, Interest Rate, Stated Percentage								12.00%
Subsequent Event [Member] \| Promissory Note [Member] \| Promissory Note, One [Member]
Debt Instrument, Face Amount							$ 490,000
Proceeds from Short-term Debt, Total							$ 400,000
Subsequent Event [Member] \| Promissory Note [Member] \| Promissory Note, Two [Member]
Debt Instrument, Face Amount			$ 480,000										$ 480,000
Proceeds from Short-term Debt, Total			$ 400,000