Note 1 - Summary of Significant Accounting Policies - Components of Intangible Assets (Details) - USD ($)	Jun. 30, 2019	Dec. 31, 2018
Gross Carrying Costs	$ 4,929,240	$ 1,195,803
Accumulated Amortization	(337,368)	(231,308)
Net Carrying Amount	4,591,872	964,495
Patents and Trademarks [Member]
Gross Carrying Costs	326,740	318,303
Accumulated Amortization	(188,698)	(182,558)
Net Carrying Amount	138,042	135,745
Licensing Agreements [Member]
Gross Carrying Costs	877,500	877,500
Accumulated Amortization	(78,000)	(48,750)
Net Carrying Amount	799,500	828,750
Developed Technology Rights [Member]
Gross Carrying Costs	2,882,000
Accumulated Amortization	(34,823)
Net Carrying Amount	2,847,177
Customer Relationships [Member]
Gross Carrying Costs	445,000
Accumulated Amortization	(35,847)
Net Carrying Amount	409,153
Trade Names [Member]
Gross Carrying Costs	398,000
Accumulated Amortization
Net Carrying Amount	$ 398,000

Accumulated amount of amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 30
-Section 50
-Paragraph 2
-Subparagraph (a)(1)
-URI http://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275

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Amount before amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 928
-SubTopic 340
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6473545&loc=d3e61844-108004

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-Subparagraph (a)(1)
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