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Note 1 - Summary of Significant Accounting Policies (Tables)
6 Months Ended
Jun. 30, 2019
Notes Tables  
Schedule of Inventory, Current [Table Text Block]
    June 30,
2019
  December 31,
2018
         
Finished goods   $
150,340
    $
58,701
 
Raw materials    
91,437
     
127,003
 
Work-In-Process    
79,099
     
55,362
 
Total   $
320,876
    $
241,066
 
Property Plant and Equipment Useful Life [Table Text Block]
   
Years
Computers and office equipment
 
3
-
7
Leasehold improvements
 
 
2
 
Manufacturing tooling
 
3
-
7
Demo equipment
 
 
3
 
Laboratory equipment  
 
4
 
Property, Plant and Equipment [Table Text Block]
    June 30,
2019
  December 31,
2018
Computers and office equipment   $
505,728
    $
204,903
 
Leasehold improvements    
188,014
     
140,114
 
Manufacturing tooling    
108,955
     
108,955
 
Demo equipment    
77,973
     
85,246
 
Laboratory equipment    
1,401,210
     
-
 
Total    
2,281,880
     
539,218
 
Less: Accumulated depreciation    
512,067
     
358,765
 
Total Fixed Assets, Net   $
1,769,813
    $
180,453
 
Schedule of Finite-Lived Intangible Assets [Table Text Block]
    6/30/2019   12/31/2018
    Gross Carrying
Costs
  Accumulated
Amortization
  Net
Carrying
Amount
  Gross Carrying
Costs
  Accumulated
Amortization
  Net
Carrying
Amount
Patents & Trademarks   $
326,740
    $
(188,698
)   $
138,042
    $
318,303
    $
(182,558
)   $
135,745
 
Licensing Fees    
877,500
     
(78,000
)    
799,500
     
877,500
     
(48,750
)    
828,750
 
Developed Technology    
2,882,000
     
(34,823
)    
2,847,177
     
-
     
-
     
-
 
Customer Relationships    
445,000
     
(35,847
)    
409,153
     
-
     
-
     
-
 
Tradename    
398,000
     
-
     
398,000
     
-
     
-
     
-
 
Total   $
4,929,240
    $
(337,368
)   $
4,591,872
    $
1,195,803
    $
(231,308
)   $
964,495
 
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]
Year ending
 
Expense
2019
 
 
181,748
 
2020
 
 
363,497
 
2021
 
 
363,497
 
2022
 
 
264,609
 
2023
 
 
215,165
 
 Thereafter
 
 
3,203,356
 
Total
 
 
4,591,872
 
Schedule of Segment Reporting Information, by Segment [Table Text Block]
    Three Months Ended June 30,   Six Months Ended June 30,
    2019   2019
    Domestic   International   Corporate/
Other
  Total   Domestic   International   Corporate/
Other
  Total
                                 
                                                                 
Revenue   $
259,082
    $
1,464
    $
25,605
    $
286,151
    $
478,743
    $
37,044
    $
25,605
    $
541,392
 
                                                                 
                                                                 
Segment Gain/(Loss)   $
(917,754
)   $
(97,552
)   $
2,480,410
    $
1,465,104
    $
(1,859,477
)   $
(196,213
)   $
227,610
    $
(1,828,080
)
    Net Assets as of,
    June 30, 2019   December 31, 2018
    Domestic   International   Corporate/
Other
  Total   Domestic   International   Corporate/
Other
  Total
Net Assets
  $
741,497
  $
34,841
  $
21,515,250
    $
22,291,588
    $
628,451
  $
41,377
  $
(616,356
)   $
53,472