Note 6 - Convertible Debt and Derivative Liability (Details Textual)					1 Months Ended	3 Months Ended
	Mar. 31, 2019 USD ($) yr $ / shares	Feb. 07, 2019 USD ($) $ / shares shares	Oct. 26, 2018	Oct. 03, 2018 $ / shares shares	Mar. 31, 2019 USD ($) yr $ / shares shares	Mar. 31, 2019 USD ($) yr $ / shares	Mar. 31, 2018 USD ($)	Mar. 22, 2019 $ / shares	Dec. 31, 2018 $ / shares	Sep. 30, 2018 USD ($)	Sep. 28, 2018 USD ($)	Dec. 28, 2017 $ / shares
Stock Issued During Period, Shares, Inducement for Bridge Loan | shares				650,000
Debt Instrument, Increase (Decrease), Net, Total						$ 9,120,000
Common Stock, Par or Stated Value Per Share | $ / shares	$ 0.01				$ 0.01	$ 0.01		$ 0.01	$ 0.01			$ 0.01
Stock Issued During Period, Value, Forebearance for Bridge Loan						$ 158,350
Debt Conversion, Converted Instrument, Amount						90,000
Embedded Derivative Financial Instruments [Member]
Derivative Liability, Total	$ 292,153				$ 292,153	292,153				$ 645,008
Unrealized Gain (Loss) on Derivatives						$ (19,408)
Maximum [Member]
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares	$ 309.50				$ 309.50	$ 309.50
Warrants in Connection with Convertible Promissory Note [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | shares				1,071,776
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares				$ 1.155
Class of Warrant or Right, Vesting Period			180 days
Warrants and Rights Outstanding, Term				5 years
Class of Warrant or Right, Fair Value per Warrant | $ / shares	$ 0.5361				$ 0.5361	$ 0.5361
Warrants and Rights Outstanding	$ 574,631				$ 574,631	$ 574,631
Warrants in Connection with Convertible Promissory Note [Member] | Measurement Input, Discount Rate [Member]
Warrants and Rights Outstanding, Measurement Input	0.0294				0.0294	0.0294
Warrants in Connection with Convertible Promissory Note [Member] | Measurement Input, Expected Term [Member]
Warrants and Rights Outstanding, Measurement Input | yr	5				5	5
Warrants in Connection with Convertible Promissory Note [Member] | Measurement Input, Price Volatility [Member]
Warrants and Rights Outstanding, Measurement Input	0.59				0.59	0.59
Securities Purchase Agreements [Member] | Convertible Promissory Note [Member]
Debt Instrument, Face Amount											$ 2,297,727
Proceeds from Notes Payable, Total	$ 500,000
Debt Instrument, Interest Rate, Stated Percentage				8.00%
Debt Instrument, Term				1 year
Debt Instrument, Convertible, Conversion Price, Percentage of Lowers Volume-weighted Average Price of Common Stock				70.00%
Debt Instrument, Convertible, Threshold Trading Days				20
Conversion Shares, Sum of Number of Conversion Shares Plus Inducement Shares | shares				2,678,328
Securities Purchase Agreements [Member] | Convertible Promissory Note [Member] | Maximum [Member]
Debt Instrument, Convertible, Conversion Price | $ / shares				$ 1
Bridge Notes [Member]
Debt Instrument, Increase (Decrease), Net, Total		$ 344,659
Long-term Debt, Total		$ 2,642,387
Stock Issued During Period, Shares, Forebearance for Bridge Loan | shares		166,667
Common Stock, Par or Stated Value Per Share | $ / shares	$ 2	$ 0.01			$ 2	$ 2
Stock Issued During Period, Value, Forebearance for Bridge Loan		$ 158,350
Debt Conversion, Converted Instrument, Amount					$ 90,000
Debt Conversion, Converted Instrument, Shares Issued | shares					159,854
Increase (Decrease) in Notes Payable, Current, Total					$ (93,826)