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The number of warrants that are fully vested and exercisable at the balance sheet date.

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Represents the shares per each unit.

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The exercise price of units as a percent of offering price.

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Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

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Exercise price per share or per unit of warrants or rights outstanding.

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Number of securities into which each warrant or right may be converted. For example, but not limited to, each warrant may be converted into two shares.

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Number of securities into which the class of warrant or right may be converted. For example, but not limited to, 500,000 warrants may be converted into 1,000,000 shares.

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Face amount or stated value per share of common stock.

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The maximum number of common shares permitted to be issued by an entity's charter and bylaws.

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Weighted-average period over which cost not yet recognized is expected to be recognized for award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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Amount of cost to be recognized for option under share-based payment arrangement.

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The cash inflow from the issuance of common stock, preferred stock, treasury stock, stock options, and other types of equity.

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Period over which grantee's right to exercise award under share-based payment arrangement is no longer contingent on satisfaction of service or performance condition, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. Includes, but is not limited to, combination of market, performance or service condition.

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The estimated dividend rate (a percentage of the share price) to be paid (expected dividends) to holders of the underlying shares over the option's term.

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The estimated measure of the percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period.

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The risk-free interest rate assumption that is used in valuing an option on its own shares.

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The weighted average grant-date fair value of options granted during the reporting period as calculated by applying the disclosed option pricing methodology.

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Number of fully vested and expected to vest exercisable options that may be converted into shares under option plan. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.

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Weighted-average exercise price, at which grantee can acquire shares reserved for issuance, for fully vested and expected to vest options outstanding. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.

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Period from grant date that an equity-based award expires, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Expected term of award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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Weighted average remaining contractual term for fully vested and expected to vest options outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.

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Per share or per unit amount of equity securities issued.

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Number of new stock issued during the period.

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Note 4 - Stockholders' Equity (Deficit), Stock Options and Warrants (Details Textual) - USD ($)	1 Months Ended	3 Months Ended		12 Months Ended
	Mar. 31, 2019	Mar. 31, 2019	Mar. 31, 2018	Dec. 31, 2018	Mar. 22, 2019	Dec. 28, 2017	Jan. 29, 2017
Common Stock, Shares Authorized	100,000,000	100,000,000		100,000,000	100,000,000	50,000,000	24,000,000
Common Stock, Par or Stated Value Per Share	$ 0.01	$ 0.01		$ 0.01	$ 0.01	$ 0.01
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate		0.00%
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate		79.80%
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number	3,346,375	3,346,375
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price	$ 1.70	$ 1.70
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term		8 years 262 days
Class of Warrant or Right Number of Warrants Vested and Exercisable	4,750,221	4,750,221
Share-based Payment Arrangement, Expense		$ 263,600	$ 226,387
Share-based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount	$ 130,839	$ 130,839
Share-based Payment Arrangement, Option [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value		$ 0.73		$ 1.01
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition		1 year 240 days
Maximum [Member]
Class of Warrant or Right, Exercise Price of Warrants or Rights	$ 309.50	$ 309.50
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate		2.76%
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term		10 years
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value		$ 0.7644
Minimum [Member]
Class of Warrant or Right, Exercise Price of Warrants or Rights	$ 0	$ 0
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate		2.41%
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term		5 years
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value		$ 0.4112
Amended and Restated 2012 Stock Incentive Plan [Member]
Common Stock, Shares Authorized					10,000,000
Equity Incentive Plan [Member] \| Maximum [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period		3 years
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period		10 years
Equity Incentive Plan [Member] \| Minimum [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period		3 years
Warrants Issued With First 2019 Registered Direct Offering [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights	692,500	692,500
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right	0.5	0.5
Class of Warrant or Right, Exercise Price of Warrants or Rights	$ 1	$ 1
The First 2019 Registered Direct Offering [Member]
Stock Issued During Period, Shares, New Issues	1,385,000
Share Per Each Unit	1	1
Shares Issued, Price Per Share	$ 0.90	$ 0.90
Proceeds from Issuance or Sale of Equity, Total		$ 1,246,608
Right to Purchase Units, Assigned to Underwriters	69,250	69,250
Units, Exercise Price Percent of Offering Price	125.00%	125.00%
Class of Warrant or Right, Issued per Unit	1.125
The Second 2019 Registered Direct Offering [Member]
Stock Issued During Period, Shares, New Issues	1,478,750
Share Per Each Unit	1	1
Shares Issued, Price Per Share	$ 0.80	$ 0.80
Proceeds from Issuance or Sale of Equity, Total		$ 1,183,101
Right to Purchase Units, Assigned to Underwriters	73,937	73,937
Units, Exercise Price Percent of Offering Price	125.00%	125.00%
Class of Warrant or Right, Issued per Unit	1
Warrants Issued With Second 2019 Registered Direct Offering [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights	739,377	739,377
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right	0.5	0.5
Class of Warrant or Right, Exercise Price of Warrants or Rights	$ 1	$ 1