Note 1 - Summary of Significant Accounting Policies (Details Textual)				1 Months Ended					3 Months Ended
	Feb. 06, 2019 USD ($)	Jan. 08, 2019 USD ($)	Nov. 30, 2018 USD ($)	Mar. 31, 2019 USD ($) $ / shares shares	Feb. 28, 2019 USD ($)	Nov. 30, 2018 USD ($)	Sep. 30, 2018 USD ($)	Jan. 31, 2018 USD ($)	Mar. 31, 2019 USD ($) $ / shares shares	Mar. 31, 2018 USD ($)	Mar. 22, 2019 $ / shares	Jan. 01, 2019 USD ($)	Dec. 31, 2018 USD ($) $ / shares shares	Dec. 28, 2017 $ / shares
Common Stock, Shares, Outstanding, Ending Balance | shares				17,360,144					17,360,144				14,091,748
Common Stock, Par or Stated Value Per Share | $ / shares				$ 0.01					$ 0.01		$ 0.01		$ 0.01	$ 0.01
Retained Earnings (Accumulated Deficit), Ending Balance				$ (66,401,129)					$ (66,401,129)				$ (63,107,945)
Cash and Cash Equivalents, at Carrying Value, Ending Balance				1,124,730					1,124,730				162,152
Stockholders' Equity, Period Increase (Decrease), Total									38,970,000
Debt Instrument, Increase (Decrease), Net, Total									9,120,000
Operating Lease, Right-of-Use Asset				333,944					333,944
Operating Lease, Liability, Current				78,819					78,819
Depreciation, Total									21,882	$ 14,496
Amortization of Intangible Assets, Total									17,644	$ 3,671
Income Tax Expense (Benefit), Total									0
Unrecognized Tax Benefits, Ending Balance				0					0
Liability for Uncertainty in Income Taxes, Current				0					$ 0
Open Tax Year									2015 2016 2017 2018
Number of Operating Segments									2
Operating Lease, Liability, Total				333,944					$ 333,944
Accounting Standards Update 2016-02 [Member]
Operating Lease, Right-of-Use Asset												$ 353,007
Operating Lease, Liability, Current												79,252
Operating Lease, Liability, Total												$ 353,007
Chief Executive Officer [Member]
Proceeds from Related Party Debt	$ 300,000	$ 950,000	$ 370,000	300,000	$ 950,000	$ 370,000
Convertible Promissory Note [Member]
Proceeds from Debt, Net of Issuance Costs							$ 1,815,000
S-3 Public Offering [Member]
Proceeds from Issuance or Sale of Equity, Total									2,100,000
Issuance or Sale of Equity, Potentially Issuable				5,000,000					$ 5,000,000
The 2018 Public Offering [Member]
Proceeds from Issuance or Sale of Equity, Total								$ 2,475,000
First S-3 Public Offering [Member]
Proceeds from Issuance or Sale of Equity, Total				1,112,000
Second S-3 Public Offering [Member]
Proceeds from Issuance or Sale of Equity, Total				$ 1,053,000
Helomics Holding Corp. [Member]
Business Combination, Step Acquisition, Equity Interest in Acquiree, Percentage										25.00%