Note 9 - Rent Obligation (Details Textual)		12 Months Ended
	Jun. 15, 2018 EUR (€) ft²	Dec. 31, 2018 USD ($)	Dec. 31, 2017 USD ($)	Feb. 01, 2018 ft²
Operating Leases, Rent Expense, Total | $		$ 69,013	$ 66,122
Corporate Office, Minnesota [Member]
Lessee, Operating Lease, Term of Contract				3 years
Area of Real Estate Property				5,773
Corporate Office, Minnesota [Member] | Office Space [Member]
Area of Real Estate Property				2,945
Corporate Office, Minnesota [Member] | Manufacturing Facility [Member]
Area of Real Estate Property				2,828
Skyline Medical Europe’s Offices Lease [Member]
Area of Real Estate Property	2,000
Lessee, Operating Lease, Monthly Rent | €	€ 3,000
Skyline Medical Europe’s Offices Lease [Member] | Office Space [Member]
Area of Real Estate Property	1,250
Skyline Medical Europe’s Offices Lease [Member] | Storage Space [Member]
Area of Real Estate Property	300