Note 1 - Summary of Significant Accounting Policies - Components of Intangible Assets (Details) - USD ($)	Dec. 31, 2018	Dec. 31, 2017
Gross Carrying Costs	$ 1,195,804	$ 264,032
Accumulated Amortization	(231,309)	(168,676)
Net Carrying Amount	964,495	95,356
Patents and Trademarks [Member]
Gross Carrying Costs	318,304	264,032
Accumulated Amortization	(182,559)	(168,676)
Net Carrying Amount	135,745	95,356
Licensing Agreements [Member]
Gross Carrying Costs	877,500
Accumulated Amortization	(48,750)
Net Carrying Amount	$ 828,750

Accumulated amount of amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 30
-Section 50
-Paragraph 2
-Subparagraph (a)(1)
-URI http://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275

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Amount before amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 928
-SubTopic 340
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6473545&loc=d3e61844-108004

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