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Note 3 - Stockholders' Deficit, Stock Options and Warrants (Details Textual) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended
Mar. 31, 2016
Aug. 31, 2015
Sep. 09, 2014
Jun. 30, 2014
Feb. 04, 2014
Jun. 30, 2015
Mar. 31, 2015
Jan. 31, 2015
Dec. 31, 2014
Nov. 30, 2014
Sep. 30, 2014
Aug. 31, 2014
Jun. 30, 2014
Mar. 31, 2014
Jan. 31, 2014
Mar. 31, 2016
Mar. 31, 2015
Mar. 31, 2014
Dec. 31, 2015
Dec. 31, 2014
Mar. 11, 2016
Jul. 24, 2015
May. 05, 2015
Jul. 31, 2014
Feb. 28, 2014
Maximum [Member]                                                  
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period                               3 years                  
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period                               10 years                  
Class of Warrant or Right, Exercise Price of Warrants or Rights $ 24.375                             $ 24.375                  
Underwriting Agreement Expenses Agreed to Reimburse the Underwriter   $ 70,000                                              
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate                                     2.35% 2.75%          
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term                                     10 years 10 years          
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price                               $ 23.85     $ 5.5695 $ 13.9195          
Minimum [Member]                                                  
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period                               3 years                  
Class of Warrant or Right, Exercise Price of Warrants or Rights $ 3.75                             $ 3.75                  
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate                                     1.63% 1.44%          
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term                                     5 years 5 years          
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price                               $ 0.17     $ 0.275 $ 3.2006          
Series A Convertible Preferred Stock [Member] | Exchange Units [Member]                                                  
Stock Issued During Period, Shares, Conversion of Convertible Securities   84,770                                              
Series A Convertible Preferred Stock [Member]                                                  
Preferred Stock, Shares Outstanding   0                                              
Class of Warrant or Right, Exercise Price of Warrants or Rights                                                 $ 24.38
Stock Issued During Period, Shares, New Issues         20,550                                        
Preferred Stock Par Value         $ 0.01                                        
Preferred Stock Stated Value         $ 100                                        
Stock Issued During Period, Value, New Issues         $ 2,055,000                                        
Series B Convertible Preferred Stock [Member] | Exchange Units [Member]                                                  
Stock Issued During Period, Shares, Conversion of Convertible Securities   1,895,010                                              
Series B Convertible Preferred Stock [Member] | Corporate Stock Transfer Inc. [Member]                                                  
Unit Agreement Number of Shares of Preferred Stock Included in Each Unit   1                                              
Series B Convertible Preferred Stock [Member]                                                  
Preferred Stock, Shares Outstanding 690,527                             690,527     1,895,010            
Convertible Preferred Stock, Shares Issued upon Conversion   1                                              
Beneficial Ownership Limitation Percentage   4.99%                                              
Preferred Stock Par Value $ 0.01                             $ 0.01     $ 0.01            
Preferred Stock, Shares Authorized 10,000,000                             10,000,000     10,000,000            
Four Lenders [Member]                                                  
Class of Warrant or Right, Number of Securities Called by Warrants or Rights                     37,440 37,440                          
Class of Warrant or Right, Exercise Price of Warrants or Rights                     $ 12.38 $ 12.38                          
Chief Executive Officer [Member]                                                  
Stock Issued During Period, Value, Stock Options Exercised                             $ 4,336                    
Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price                             $ 1.25                    
Dr.Samuel Herschkowitz [Member]                                                  
Class of Warrant or Right, Number of Securities Called by Warrants or Rights                                                 1,482
Class of Warrant or Right, Exercise Price of Warrants or Rights                                                 $ 20.25
Two Lenders [Member]                                                  
Class of Warrant or Right, Number of Securities Called by Warrants or Rights                                               28,986  
Class of Warrant or Right, Exercise Price of Warrants or Rights                                               $ 12.38  
Purchasers [Member]                                                  
Class of Warrant or Right, Number of Securities Called by Warrants or Rights                       61,539                          
Class of Warrant or Right, Exercise Price of Warrants or Rights                       $ 24.38                          
Stock Issued During Period, Shares, Conversion of Convertible Securities           3,121 3,121 3,122 1,559   1,561                            
Preferred Stock, Dividend Rate, Percentage           6.00% 6.00%   6.00%   6.00%                            
Conversion of Stock Price Per Share           $ 9.75 $ 9.75 $ 9.75                                  
Number of Preferred Stock Share holders           16 16 16 16   16           16     16          
Maximum Number of Days Not Listed on Stock Market                       180 days                          
Preferred Stock Conversion Price Per Share               $ 19.50 $ 19.50   $ 19.50                            
Exchange Units [Member] | Common Stock [Member]                                                  
Stock Issued During Period, Shares, Conversion of Convertible Securities   1,895,010                                              
Exchange Units [Member] | Series A Warrants [Member]                                                  
Stock Issued During Period, Shares, Conversion of Convertible Securities   7,580,040                                              
Exchange Units [Member] | Corporate Stock Transfer Inc. [Member]                                                  
Unit Purchase Option Units Issued   228,343                                              
Unit Purchase Option Number of Units Available for Underwriter to Purchase, Percentage   5.00%                                              
Unit Purchase Option Number of Units Available For Underwriter to Purchase   83,333                                              
Unit Purchase Option Exercise Price, Percentage   125.00%                                              
Unit Purchase Option Exercise Price   $ 11.25                                              
Exchange Units [Member]                                                  
Unit Purchase Option Units Issued   228,343                                              
Stock Issued During Period, Shares, Conversion of Convertible Securities   1,895,010                                              
Common Stock [Member]                                                  
Stock Issued During Period, Shares, New Issues                                     1,666,667            
Share Price                                             $ 125.25    
Stock Issued During Period Shares Warrants Exercised                               46,815,822     3,000            
Stock Issued During Period, Value, New Issues                                     $ 16,667            
Stock Issued During Period Shares Preferred Stock Conversion                               1,204,483     228,343            
Warrant [Member]                                                  
Cashless Exercise of Common Stock Warrants, Total                                   15,442              
Series A Warrants [Member] | Corporate Stock Transfer Inc. [Member] | Scenario, All Outstanding Warrants Exercised at Minimum Bid Price [Member]                                                  
Stock Issued During Period Shares Warrants Exercised 28,478,031                                                
Series A Warrants [Member] | Corporate Stock Transfer Inc. [Member]                                                  
Class of Warrant or Right, Number of Securities Called by Warrants or Rights 47,682,012                             47,682,012                  
Class of Warrant or Right, Exercise Price of Warrants or Rights   $ 4.95                                              
Unit Agreement Number of Warrants Included in Each Unit   4                                              
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right   1                                              
Cash Less Exercise Formula Definition of Letter C in the Formula Closing Bid Price Number of Trading Days Prior to the Time of Exercise   2 days                                              
Cash Less Exercise Formula Closing Bid Price Per Share Minimum to Be Used in the Formula                                         $ 0.43        
Warrants Option to Settle in Cash Fair Value Disclosure $ 4.3217                             $ 4.3217                  
Class of Warrant or Right Exercised During Period 4,746,405                                                
Class of Warrant or Right, Outstanding 2,833,635                             2,833,635                  
Class of Warrant or Right Cash less Exercise Common Stock Price That Would Result in a Dilutive Exercise $ 0.43                             $ 0.43                  
Beneficial Ownership Limitation Percentage   4.99%                                              
Class of Warrant or Right Period Over Which Additional Adjustments to Price and Number of Shares May Be Made   3 years                                              
Corporate Stock Transfer Inc. [Member]                                                  
Unit Agreement Number of Shares of Common Stock Included in Each Unit   1                                              
Common Stock, Par or Stated Value Per Share   $ 0.01                                              
The Convertible Notes [Member]                                                  
Debt Instrument Redemption Principal Amount   $ 933,074                                              
Debt Instrument Redemption Premium Percentage   40.00%                                              
Debt Instrument Redemption Price   $ 1,548,792                                              
Debt Instrument Redemption Amount Paid to Affiliates   $ 167,031                                              
SOK Partners LLC [Member]                                                  
Class of Warrant or Right, Number of Securities Called by Warrants or Rights     4,831 5,431                 5,431                        
Class of Warrant or Right, Exercise Price of Warrants or Rights     $ 12.38 $ 12.38                 $ 12.38                        
Percentage of Reduction to Warrant Agreement     11.00%                                            
Option Granted to Underwriter to Purchase Additional Units Additional Units Purchased   0                                              
Percentage Reduction to Number of Warrants                     11.00% 11.00%                       11.00%  
Class of Warrant or Right, Number of Securities Called by Warrants or Rights                             21,538                   21,538
Class of Warrant or Right, Exercise Price of Warrants or Rights                           $ 11.25       $ 11.25              
Stock Issued During Period, Shares, New Issues   1,666,667               13,700                              
Shares Issued, Price Per Share   $ 9                                              
Underwriter Price   8.28                                              
Underwriting Discount   $ 0.72                                              
Underwriting Commission   8.00%                                              
Proceeds from Issuance or Sale of Equity   $ 13,800,000                                              
Option Granted to Underwriter to Purchase Additional Units Period   45 days                                              
Option Granted to Underwriter to Purchase Additional Units Number of Units Granted   250,000                                              
Underwriting Agreement Non-accountable Expense Allowance Percentage   1.00%                                              
Common Stock, Par or Stated Value Per Share $ 0.01                 $ 0.01           $ 0.01     $ 0.01            
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right 10.05                             10.05                  
Share Price $ 0.20                             $ 0.20                  
Class of Warrant or Right, Outstanding 3,331,072                             3,331,072                  
Cashless Exercise of Common Stock Warrants, Total                           3,333                      
Stock Issued During Period, Value, New Issues                                     $ 13,060,880            
Preferred Stock, Dividend Rate, Percentage       6.00%                   6.00%                      
Conversion of Stock Price Per Share                           $ 19.50                      
Stock Issued During Period Shares Preferred Stock Conversion       1,561                   970                      
Number of Preferred Stock Share holders       16                 16 16       16              
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period                         3,725 4,444                      
Preferred Stock, Par or Stated Value Per Share       $ 19.50                 $ 19.50                        
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate                                     0.00% 0.00%          
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum                                     59.00% 59.00%          
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum                                     66.00% 66.00%          
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number 868,570                             868,570                  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price $ 4.73                             $ 4.73                  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term                               8 years 102 days                  
Allocated Share-based Compensation Expense                               $ 37,775 $ 72,116                
Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options $ 0                             $ 0                  
Common Stock, Shares Authorized 100,000,000                             100,000,000     100,000,000     100,000,000      
Preferred Stock, Shares Authorized                                           20,000,000