Note 3 – Stockholders’ Equity (Deficit), Stock Options and Warrants (Tables)

12 Months Ended

Dec. 31, 2015

Stockholders' Equity Note [Abstract]

Schedule of Share-based Compensation, Activity [Table Text Block]

	Stock Options					Warrants
	Number of Shares			Average Exercise Price		Number of Shares			Average Exercise Price
Outstanding at December 31, 2013		385,733		$	6.75		461,920		$	10.50
Issued		75,683			8.12		161,375			3.81
Expired		(7,879	)		23.58		(81,851	)		13.54
Exercised		(4,936	)		1.76		(40,722	)		8.38
Outstanding at December 31, 2014		448,601		$	7.51		500,722		$	7.95
Issued		354,253			2.76		7,581,722			4.95
Cancelled		(19,136	)		11.73		(1,967	)		11.34
Exercised		-			-		(3,000	)		4.95
Outstanding at December 31, 2015		783,718		$	5.33		8,077,477		$	5.14

Schedule of Share-based Compensation, Shares Authorized under Stock Option and Warrant Plans, by Exercise Price Range [Table Text Block]

Range of Exercise Prices	Shares		Weighted Average Remaining Life
Options:
$0.75		7,333		5.52
$2.63		250,481		9.81
$2.94		30,614		10.01
$3.10		59,681		9.50
$3.21		6,232		9.76
$3.45		7,245		9.25
$4.875		134		7.20
$5.25		2,031		6.69
$5.625		192,000		7.21
$5.925		23,206		7.22
$6.00		123,998		6.63
$6.50		3,845		9.01
$8.25		3,636		8.76
$9.9375		3,019		7.54
$10.50		3,238		7.54
$11.25		13,666		7.09
$12.75		67		7.36
$13.875		2,160		8.25
$71.25		40,261		8.19
$18.75		3,334		8.15
$20.25		4,940		8.01
$21.75		1,336		7.77
$23.85		1,260		7.75
Total		783,718
Warrants:
$4.95		7,577,040		4.67
$6.00		102,857		2.20
$9.00		2,666		2.07
$9.75		63,227		3.59
$11.25		203,801		2.02
$12.375		71,257		3.61
$12.38		5,557		3.85
$13.50		4,444		2.47
$14.85		23,612		2.41
$20.25		1,481		3.13
$24.375		21,535		3.10
Total		8,077,477

Disclosure of Share-based Compensation Arrangements by Share-based Payment Award [Table Text Block]

Year	Shares		Price
2011		11,666			.75
2012		126,029		5.25	–	6.00
2013		232,756		4.875	–	23.85
2014		59,013		6.50	–	18.75
2015		354,253		2.63	–	3.45
Total		783,718	$	.75	–	23.85

Year	Shares		Price
2012		69,801		11.25	–	15.00
2013		267,579		6.00	–	14.85
2014		161,375		12.375	–	24.375
2015		7,578,722			4.95
Total		8,077,477	$	4.95	–	24.375