Nature of Business and Basis of Presentation - Additional Information (Detail) - USD ($) $ in Thousands		1 Months Ended	3 Months Ended				6 Months Ended
	Jun. 05, 2022	Apr. 30, 2021	Jun. 30, 2022	Mar. 31, 2022	Jun. 30, 2021	Mar. 31, 2021	Jun. 30, 2022	Jun. 30, 2021	Feb. 28, 2022	Dec. 31, 2021
Nature of Business [Line Items]
Accumulated deficit			$ (205,539)			$ (156,492)	$ (205,539)			$ (187,313)
Net loss			(4,845)	$ (13,381)	$ (10,454)	$ (8,682)	(18,226)	$ (19,136)
Workforce reduced									60.00%
Public Float, Increased			75,000				75,000
Janssen Pharmaceutica NV
Nature of Business [Line Items]
Asset purchase agreement price	$ 26,000
At The Market Offering [Member] | New Sales Agreement With Jefferies Llc [Member]
Nature of Business [Line Items]
Common Stock, Value, Subscriptions			$ 59,600				$ 59,600			$ 60,000
Percentage of commission on gross proceeds of common stock sold		3.00%
At The Market Offering [Member] | Prior Sales Agreement With Jefferies Llc [Member]
Nature of Business [Line Items]
Common Stock, Value, Subscriptions		$ 60,000
Sale of Stock, Number of Shares Issued							216,332
Sale Of Stock Consideration Received On Transaction, net							$ 400