Net Loss Per Share (Tables)

12 Months Ended

Dec. 31, 2018

Computation of Basic and Diluted Net Loss per Share

The following table summarizes the computation of basic and diluted net loss per share (in thousands, except share and per share data):


	Years Ended December 31,
	2018			2017			2016
Net loss	$	(49,205	)	$	(36,658	)	$	(31,778	)
Weighted average shares outstanding		30,051,961			29,424,360			28,492,091
Less: weighted average shares subject to repurchase		—			(306	)		(7,088	)
Weighted average shares used to compute basic and diluted net loss per share		30,051,961			29,424,054			28,485,003
Net loss per share, basic and diluted	$	(1.64	)	$	(1.25	)	$	(1.12	)

Computation of Potentially Dilutive Securities Outstanding Excluded from Computation of Diluted Shares

The following potentially dilutive securities outstanding at the end of the periods presented have been excluded from the computation of diluted shares outstanding:

	December 31,
	2018		2017		2016
Unreleased restricted stock		1,010,123		720,840		345,555
Options to purchase common stock		2,529,740		2,559,972		2,821,227
Convertible senior notes		1,790,033		1,790,033		1,790,033
Warrants related to the issuance of convertible senior notes		1,790,033		1,790,033		1,790,033
Total		7,119,929		6,860,878		6,746,848