Collaboration agreements - Summary of Contract Assets and Liabilities (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Contract Liabilities [Roll Forward]
Balance at Beginning of Period	$ 125,314	$ 147,653
Additions	8,616	5,517
Deductions	(32,298)	(27,856)
Balance at End of Period	101,632	125,314
Amounts included in the contract liability at the beginning of the period	$ 27,312	$ 27,870