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Collaboration agreements - Johnson & Johnson (Details) $ in Thousands	1 Months Ended	12 Months Ended
	Feb. 28, 2022 USD ($) target license performanceObligation	Dec. 31, 2024 USD ($) target	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)
Collaboration agreements
Collaboration revenue		$ 40,497	$ 36,855	$ 26,581
Deferred revenue		$ 101,632	125,314	147,653
Johnson & Johnson Agreement
Collaboration agreements
Number of targets designated \| target	3	1
Upfront payment received	$ 40,000
Number of licenses \| license	2
Number of targets terminated \| target		2
Performance obligations identified \| performanceObligation	7
Revised transaction price	$ 40,000	$ 56,000
Number of targets initiated \| target		1
Collaboration revenue		$ 19,100	16,600	24,200
Deferred revenue		3,200	10,400
Johnson & Johnson Agreement \| Development Milestone Achieved
Collaboration agreements
Collaboration revenue		8,000	$ 2,000	$ 2,000
Johnson & Johnson Agreement \| Licenses and Research Services
Collaboration agreements
Collaboration revenue		2,600
Johnson & Johnson Agreement \| Development and Regulatory
Collaboration agreements
Aggregate milestones	169,000
Johnson & Johnson Agreement \| Commercial
Collaboration agreements
Aggregate milestones	$ 175,000
Johnson And Johnson 2024 CSA Arrangement
Collaboration agreements
Revised transaction price		8,500
Collaboration revenue		$ 3,800