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Net loss per share
12 Months Ended
Dec. 31, 2024
Earnings Per Share [Abstract]  
Net loss per share Net loss per share
Basic net loss per share of common stock is calculated by dividing the net loss attributable to common stockholders by the weighted-average number of shares of common stock outstanding during the period, without further consideration for potentially dilutive securities. In accordance with ASC 260, Earnings Per Share, the Pre-Funded Warrants are included in the computation of basic net loss per share because the exercise price is negligible and they are fully vested and exercisable at any time after the original issuance date, subject to certain limitations. Diluted net loss per share is computed by dividing the net loss attributable to common stockholders by the weighted-average number of shares of common stock and potentially dilutive securities outstanding for the period determined using the treasury stock method.

For purposes of the diluted net loss per share calculation, stock options, unvested RSUs and warrants to purchase common stock are considered to be potentially dilutive securities, but are excluded from the calculation of diluted net loss per share because their effect would be anti-dilutive and therefore, basic and diluted net loss per share were the same for all periods presented.

The following table sets forth the outstanding potentially dilutive securities that have been excluded from the calculation of diluted net loss per share because to include them would be anti-dilutive (in common stock equivalent shares):

Year ended December 31,
202420232022
Stock options12,219,248 10,902,845 10,051,283 
Unvested restricted stock units3,933,032 3,834,108 1,870,791 
Warrants— — 22,590 
16,152,280 14,736,953 11,944,664