Stock-based compensation - Schedule of Stock-Based Compensation Expense as Reflected in the Company's Condensed Consolidated Statements of Operations and Comprehensive Loss (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Stock options
Share-based compensation expense	$ 4,425	$ 6,643	$ 9,085	$ 13,050
Research and development
Stock options
Share-based compensation expense	2,362	3,396	4,890	6,728
General and administrative
Stock options
Share-based compensation expense	$ 2,063	$ 3,247	$ 4,195	$ 6,322