Collaboration agreements - Contract Assets and Liabilities (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Contract liabilities
Balance at Beginning of Period			$ 125,314	$ 147,653
Additions			2,940	808
Deductions			11,338	13,764
Balance at End of Period	$ 116,916	$ 134,697	116,916	134,697
Amounts included in the contract liability at the beginning of the period	$ 2,293	$ 8,497	$ 11,231	$ 13,607