Stock-based compensation - Schedule of Stock-Based Compensation Expense as Reflected in the Company's Condensed Consolidated Statements of Operations and Comprehensive Loss (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2024	Mar. 31, 2023
Stock options
Share-based compensation expense	$ 4,660	$ 6,407
Research and development
Stock options
Share-based compensation expense	2,528	3,332
General and administrative
Stock options
Share-based compensation expense	$ 2,132	$ 3,075