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Income taxes - Reconciliation (Details)
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Effective Income Tax Rate Reconciliation, Percent [Abstract]    
Statutory US Federal Rate 21.00% 21.00%
State taxes, net of federal benefit 5.50% 5.70%
Permanent differences (0.10%) (0.10%)
General business credits 4.00% 4.40%
Stock compensation (1.90%) (1.40%)
Change in valuation allowance (28.50%) (29.60%)
Income tax benefit 0.00% 0.00%