Collaboration agreements - GlaxoSmithKline (Details) $ in Thousands	1 Months Ended	12 Months Ended
	Aug. 31, 2022 USD ($)	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)	Aug. 06, 2022 USD ($) performanceObligation
Collaboration agreements
Collaboration revenue		$ 36,855	$ 26,581	$ 43
Deferred revenue		125,314	147,653	$ 3,944
GSK Agreement
Collaboration agreements
Upfront payment received	$ 100,000
Collaboration arrangement, potential option exercise receivable	90,000
Revised transaction price					$ 100,000
Performance obligations identified | performanceObligation					2
Collaboration revenue		3,400	2,000
Deferred revenue		$ 94,600	$ 98,000
GSK Agreement | Developmental, Commercial, And Regulatory
Collaboration agreements
Aggregate milestones	1,300,000
GSK Agreement | Early Clinical Development
Collaboration agreements
Aggregate milestones	$ 30,000