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Summary of significant accounting policies - Property and Equipment (Details) - USD ($)
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Property, equipment and software, net      
Asset impairment charges $ 0 $ 0 $ 0
Computer equipment, office equipment and software      
Property, equipment and software, net      
Estimated useful life 3 years    
Laboratory equipment      
Property, equipment and software, net      
Estimated useful life 5 years