Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022
Cash flows from operating activities
Net loss	$ (110,470)	$ (99,477)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation	643	432
Net amortization of premiums and discounts on marketable securities	(3,191)	(104)
Stock-based compensation	13,050	10,833
Other non-cash items	319	381
Changes in operating assets and liabilities:
Accounts receivable	30,000	0
Prepaid expenses and other current assets	(1,992)	419
Accounts payable	3,337	(4,383)
Accrued expenses	(9,502)	4,904
Operating lease right-of-use assets	1,344	1,493
Operating lease liabilities	(1,421)	(1,199)
Deferred revenue	(12,956)	33,970
Net cash used in operating activities	(90,839)	(52,731)
Cash flows from investing activities
Maturities of marketable securities	119,000	0
Purchase of marketable securities	(121,733)	(89,813)
Purchase of property and equipment	(1,310)	(986)
Net cash used in investing activities	(4,043)	(90,799)
Cash flows from financing activities
Net proceeds from at-the-market facilities	93,620	100,361
Proceeds from exercise of stock options	427	96
Proceeds from purchases of common stock under ESPP	963	606
Payment of debt issuance costs	(150)	0
Payments under finance lease obligations	(131)	(142)
Net cash provided by financing activities	94,729	100,921
Decrease in cash, cash equivalents and restricted cash	(153)	(42,609)
Cash, cash equivalents and restricted cash, beginning of period	129,363	178,425
Cash, cash equivalents and restricted cash, end of period	129,210	135,816
Supplemental disclosures of non-cash activities:
Purchases of property and equipment in accounts payable and accrued expenses	367	333
Common stock issuance costs in accounts payable and accrued expenses	81	0
Cash paid for interest	1,637	1,100
Right-of-use assets obtained in exchange for operating lease liabilities	$ 0	$ 298