Condensed Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Balance at beginning of period (in shares) at Dec. 31, 2021		73,709,056
Balance at beginning of period at Dec. 31, 2021	$ 121,741	$ 7	$ 572,213	$ 0	$ (450,479)
Increase (Decrease) in Stockholders' Equity
Issuance of common stock under public offering, net of issuance costs (in shares)		13,169,903
Issuance of common stock under public offering, net of issuance costs	60,462	$ 2	60,460
Exercise of stock options (in shares)		26,951
Exercise of stock options	96		96
Vesting of restricted stock units, net of employee tax obligations (in shares)		167,174
Stock-based compensation expense	5,485		5,485
Net loss	(47,258)				(47,258)
Balance at end of period (in shares) at Mar. 31, 2022		87,073,084
Balance at end of period at Mar. 31, 2022	140,526	$ 9	638,254	0	(497,737)
Balance at beginning of period (in shares) at Dec. 31, 2021		73,709,056
Balance at beginning of period at Dec. 31, 2021	121,741	$ 7	572,213	0	(450,479)
Increase (Decrease) in Stockholders' Equity
Net loss	(99,477)
Balance at end of period (in shares) at Jun. 30, 2022		97,166,354
Balance at end of period at Jun. 30, 2022	134,034	$ 10	684,106	(126)	(549,956)
Balance at beginning of period (in shares) at Mar. 31, 2022		87,073,084
Balance at beginning of period at Mar. 31, 2022	140,526	$ 9	638,254	0	(497,737)
Increase (Decrease) in Stockholders' Equity
Issuance of common stock under public offering, net of issuance costs (in shares)		9,904,964
Issuance of common stock under public offering, net of issuance costs	39,899	$ 1	39,898
Vesting of restricted stock units, net of employee tax obligations (in shares)		17,417
Purchase of common stock under ESPP (in shares)		154,235
Purchase of common stock under ESPP	606		606
Stock-based compensation expense	5,348		5,348
Other comprehensive gain (loss)	(126)			(126)
Net loss	(52,219)				(52,219)
Balance at end of period (in shares) at Jun. 30, 2022		97,166,354
Balance at end of period at Jun. 30, 2022	134,034	$ 10	684,106	(126)	(549,956)
Balance at beginning of period (in shares) at Dec. 31, 2022		105,144,864
Balance at beginning of period at Dec. 31, 2022	92,057	$ 11	746,889	(152)	(654,691)
Increase (Decrease) in Stockholders' Equity
Issuance of common stock under public offering, net of issuance costs (in shares)		3,535,093
Issuance of common stock under public offering, net of issuance costs	21,795		21,795
Exercise of stock options (in shares)		8,826
Exercise of stock options	34		34
Vesting of restricted stock units, net of employee tax obligations (in shares)		372,291
Stock-based compensation expense	6,407		6,407
Other comprehensive gain (loss)	164			164
Net loss	(56,163)				(56,163)
Balance at end of period (in shares) at Mar. 31, 2023		109,061,074
Balance at end of period at Mar. 31, 2023	64,294	$ 11	775,125	12	(710,854)
Balance at beginning of period (in shares) at Dec. 31, 2022		105,144,864
Balance at beginning of period at Dec. 31, 2022	$ 92,057	$ 11	746,889	(152)	(654,691)
Increase (Decrease) in Stockholders' Equity
Exercise of stock options (in shares)	97,596
Net loss	$ (110,470)
Balance at end of period (in shares) at Jun. 30, 2023		120,459,232
Balance at end of period at Jun. 30, 2023	89,800	$ 12	854,998	(49)	(765,161)
Balance at beginning of period (in shares) at Mar. 31, 2023		109,061,074
Balance at beginning of period at Mar. 31, 2023	64,294	$ 11	775,125	12	(710,854)
Increase (Decrease) in Stockholders' Equity
Issuance of common stock under public offering, net of issuance costs (in shares)		10,929,438
Issuance of common stock under public offering, net of issuance costs	71,875	$ 1	71,874
Exercise of stock options (in shares)		88,770
Exercise of stock options	393		393
Vesting of restricted stock units, net of employee tax obligations (in shares)		88,690
Purchase of common stock under ESPP (in shares)		291,260
Purchase of common stock under ESPP	963		963
Stock-based compensation expense	6,643		6,643
Other comprehensive gain (loss)	(61)			(61)
Net loss	(54,307)				(54,307)
Balance at end of period (in shares) at Jun. 30, 2023		120,459,232
Balance at end of period at Jun. 30, 2023	$ 89,800	$ 12	$ 854,998	$ (49)	$ (765,161)