Collaboration agreements - Janssen Biotech (Details) $ in Thousands	1 Months Ended	3 Months Ended
	Feb. 28, 2022 USD ($) target	Mar. 31, 2023 USD ($)	Mar. 31, 2022 USD ($)	Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)
Collaboration agreements
Collaboration revenue		$ 7,802	$ 2,036
Deferred revenue		144,351	42,198	$ 147,653	$ 3,944
Janssen Agreement
Collaboration agreements
Number of targets designated | target	3
Upfront payment received	$ 40,000
Collaboration revenue		1,500	$ 1,700
Deferred revenue		$ 16,200		$ 15,800