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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Income Statement [Abstract]      
Collaboration revenue $ 26,581 $ 43 $ 828
Operating expenses:      
Research and development 173,385 132,013 67,036
General and administrative 56,963 36,888 21,902
Total operating expenses 230,348 168,901 88,938
Other income (expense):      
Interest income 2,883 65 424
Interest expense (3,328) (1,267) (359)
Total other income (expense), net (445) (1,202) 65
Net loss (204,212) (170,060) (88,045)
Other comprehensive loss:      
Unrealized loss on marketable securities (152) 0 (25)
Comprehensive loss (204,364) (170,060) (88,070)
Net loss attributable to common stockholders - basic (204,212) (170,060) (88,045)
Net loss attributable to common stockholders - diluted $ (204,212) $ (170,060) $ (88,045)
Net loss per share attributable to common stockholders — basic (in dollars per share) $ (2.18) $ (2.41) $ (1.43)
Net loss per share attributable to common stockholders — diluted (in dollars per share) $ (2.18) $ (2.41) $ (1.43)
Weighted-average number of shares of common stock used in net loss per share attributable to common stockholders — basic (in shares) 93,654,243 70,580,949 61,485,205
Weighted-average number of shares of common stock used in net loss per share attributable to common stockholders — diluted (in shares) 93,654,243 70,580,949 61,485,205