Collaboration Agreements - Janssen (Details) $ in Thousands	1 Months Ended	10 Months Ended	12 Months Ended
	Feb. 28, 2022 USD ($) target	Dec. 31, 2022 USD ($)	Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)
Collaboration agreements
Collaboration revenue			$ 26,581	$ 43	$ 828
Deferred revenue		$ 147,653	147,653	$ 3,944	$ 3,987
Janssen Agreement
Collaboration agreements
Number of targets designated | target	3
Upfront payment received	$ 40,000
Revised transaction price	40,000	42,000	42,000
Transaction price adjustment		2,000
Collaboration revenue			24,200
Deferred revenue		$ 15,800	$ 15,800
Janssen Agreement | Development and Regulatory
Collaboration agreements
Aggregate milestones	505,000
Janssen Agreement | Commercial
Collaboration agreements
Aggregate milestones	$ 530,000