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Stock-based compensation - Inducement awards narrative (Details) - shares
Mar. 31, 2022
Feb. 28, 2022
Dec. 31, 2021
Stock options      
Number of shares outstanding (in shares) 10,028,741   8,342,429
Inducement Award Program      
Stock options      
Number of shares outstanding (in shares) 757,500    
Number of shares authorized (in shares)   2,000,000