Collaboration agreements - Janssen Biotech (Details)	1 Months Ended	3 Months Ended
	Feb. 28, 2022 USD ($) target	Mar. 31, 2022 USD ($)	Mar. 31, 2021 USD ($)
Collaboration agreements
Collaboration revenue		$ 2,036,000	$ 11,000
Janssen Agreement
Collaboration agreements
Proceeds from Collaborators	$ 40,000,000
Deferred revenue		38,300,000
Remaining performance obligation		38,300,000
Contract assets		0
Number of targets designated | target	3
Janssen Agreement | Limited services
Collaboration agreements
Collaboration revenue		$ 1,700,000
Development and Regulatory | Janssen Agreement
Collaboration agreements
Collaboration Arrangements, Maximum Aggregate Milestones	$ 505,000,000
Commercial | Janssen Agreement
Collaboration agreements
Collaboration Arrangements, Maximum Aggregate Milestones	$ 530,000,000