Consolidated Statements of Stockholders' Equity (Parenthetical) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Issuance costs			$ 5,587
Exercise of stock options (in shares)	421,381
Exercise of stock options	$ 1,837	$ 3,138
Common Stock
Exercise of stock options (in shares)	421,381	697,428
Additional Paid-in Capital
Exercise of stock options	$ 1,837	$ 3,138
At market equity offering program (2018 ATM)
Issuance costs		2,176
Public Stock Offering
Issuance costs		$ 10,809
At Market Equity Offering Program (2020 ATM)
Issuance costs	$ 988