Accrued Expenses (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Accrued Liabilities, Current [Abstract]
Accrued manufacturing expenses	$ 8,476	$ 4,157
Accrued clinical expenses	7,879	5,126
Accrued preclinical expenses	3,848	619
Accrued payroll and related expenses	7,319	5,412
Accrued professional fees	909	757
Accrued other	285	75
Total	$ 28,716	$ 16,146