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Collaboration agreements - 2015 Agreement - Accounting (Details) - 2015 Amended Tokeda Agreement
$ in Thousands
1 Months Ended
Jan. 31, 2015
USD ($)
Accounting analysis  
Amount of additional payment to be received in connection with options to obtain licenses for third and fourth designated targets $ 0
Total arrangement consideration 16,697
Upfront payment received 9,000
Expected fees for research services 5,776
Remaining deferred revenue 1,921
Exclusive development and commercialization license and related research services, First designated target  
Accounting analysis  
Selling price allocation 4,308
Research license and related services, Second designated target  
Accounting analysis  
Selling price allocation 1,611
Research license and related services, Third designated target  
Accounting analysis  
Selling price allocation 1,611
Research license and related services, Fourth designated target  
Accounting analysis  
Selling price allocation 1,611
Replacement right, First or second designated target  
Accounting analysis  
Selling price allocation 388
Discount on exclusive license, Second designated target  
Accounting analysis  
Selling price allocation 524
Exclusive development and commercialization license and related research services, Third designated target  
Accounting analysis  
Selling price allocation 3,105
Exclusive development and commercialization license and related research services, Fourth designated target  
Accounting analysis  
Selling price allocation 3,105
Future technological improvements  
Accounting analysis  
Selling price allocation 262
Joint research committee services, Takeda  
Accounting analysis  
Selling price allocation $ 174