0001104659-22-022959.txt : 20220214 0001104659-22-022959.hdr.sgml : 20220214 20220214163724 ACCESSION NUMBER: 0001104659-22-022959 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20211231 FILED AS OF DATE: 20220214 DATE AS OF CHANGE: 20220214 EFFECTIVENESS DATE: 20220214 FILER: COMPANY DATA: COMPANY CONFORMED NAME: PFM Health Sciences, LP CENTRAL INDEX KEY: 0001442756 IRS NUMBER: 262000428 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-13169 FILM NUMBER: 22633285 BUSINESS ADDRESS: STREET 1: 475 SANSOME STREET STREET 2: SUITE 1720 CITY: SAN FRANCISCO STATE: CA ZIP: 94111 BUSINESS PHONE: 415-281-1022 MAIL ADDRESS: STREET 1: 475 SANSOME STREET STREET 2: SUITE 1720 CITY: SAN FRANCISCO STATE: CA ZIP: 94111 FORMER COMPANY: FORMER CONFORMED NAME: Partner Fund Management, L.P. DATE OF NAME CHANGE: 20080812 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001442756 XXXXXXXX 12-31-2021 12-31-2021 false PFM Health Sciences, LP

475 Sansome Street Suite 1720 San Francisco CA 94111

13F HOLDINGS REPORT 028-13169 N Darin Sadow 415-281-1000 /s/ Darin Sadow San Francisco CA 02-14-2022 0 71 2937030 INFORMATION TABLE 2 infotable.xml ABBVIE INC COM 00287Y109 124094 916496 SH DFND 0 916496 0 ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 12004 3201066 SH DFND 0 3201066 0 AERIE PHARMACEUTICALS INC COM 00771V108 7642 1088566 SH DFND 0 1088566 0 AERIE PHARMACEUTICALS INC NOTE 1.500%10/0 00771VAB4 40252 48150000 PRN DFND 0 48150000 0 ALLENA PHARMACEUTICALS COM 018119107 168 284285 SH DFND 0 284285 0 ANTHEM INC COM 036752103 19809 42734 SH DFND 0 42734 0 ARCUS BIOSCIENCES INC COM 03969F109 138853 3431010 SH DFND 0 3431010 0 ASTRAZENECA PLC SPONSORED ADR 046353108 45770 785748 SH DFND 0 785748 0 AVANTOR INC COM 05352A100 87637 2079657 SH DFND 0 2079657 0 BCLS ACQUISITION CORP COM CL A G0904B105 4548 464103 SH DFND 0 464103 0 BIOMARIN PHARMACEUTICAL INC COM 09061G101 41077 464940 SH DFND 0 464940 0 BIOMARIN PHARMACEUTICAL INC NOTE 0.599% 8/0 09061GAH4 48118 45910000 PRN DFND 0 45910000 0 BUTTERFLY NETWORK INC COM CL A 124155102 12231 1828311 SH DFND 0 1828311 0 CANO HEALTH INC COM CL A 13781Y103 17059 1914639 SH DFND 0 1914639 0 CARDINAL HEALTH INC COM 14149Y108 32942 639783 SH DFND 0 639783 0 CARIBOU BIOSCIENCES INC COM 142038108 59418 4092309 SH DFND 0 4092309 0 CATALENT INC COM 148806102 41827 326700 SH DFND 0 326700 0 CENTENE CORP DEL COM 15135B101 91668 1112480 SH DFND 0 1112480 0 CYTOKINETICS INC COM NEW 23282W605 112355 2465016 SH DFND 0 2465016 0 DANAHER CORPORATION COM 235851102 57804 175690 SH DFND 0 175690 0 DEXCOM INC COM 252131107 2400 4469 SH DFND 0 4469 0 DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 53542 3805370 SH DFND 0 3805370 0 EDWARDS LIFESCIENCES CORP COM 28176E108 48386 373492 SH DFND 0 373492 0 ERASCA INC COM 29479A108 76954 5191405 SH DFND 0 5191405 0 FLUIDIGM CORP DEL COM 34385P108 3844 980505 SH DFND 0 980505 0 GILEAD SCIENCES INC COM 375558103 5590 76993 SH DFND 0 76993 0 HCA HEALTHCARE INC COM 40412C101 50259 195621 SH DFND 0 195621 0 HERON THERAPEUTICS INC COM 427746102 32068 3512348 SH DFND 0 3512348 0 HORIZON THERAPEUTICS PUB L SHS G46188101 117657 1091840 SH DFND 0 1091840 0 HUMANA INC COM 444859102 64671 139420 SH DFND 0 139420 0 ICON PLC SHS G4705A100 48989 158183 SH DFND 0 158183 0 ICU MED INC COM 44930G107 52354 220587 SH DFND 0 220587 0 INCYTE CORP COM 45337C102 9500 129428 SH DFND 0 129428 0 INTELLIA THERAPEUTICS INC COM 45826J105 21073 178222 SH DFND 0 178222 0 IO BIOTECH INC COM 449778109 7744 1362144 SH DFND 0 1362144 0 IQVIA HLDGS INC COM 46266C105 67160 238039 SH DFND 0 238039 0 IRHYTHM TECHNOLOGIES INC COM 450056106 61667 523982 SH DFND 0 523982 0 ISHARES TR CALL 464287906 41635 272800 SH Call DFND 0 272800 0 IVERIC BIO INC COM 46583P102 16807 1005216 SH DFND 0 1005216 0 JIYA ACQUISITION CORP COM CL A 47760M102 4534 464103 SH DFND 0 464103 0 JOHNSON & JOHNSON COM 478160104 55593 324972 SH DFND 0 324972 0 JOUNCE THERAPEUTICS INC COM 481116101 33173 3972868 SH DFND 0 3972868 0 KARUNA THERAPEUTICS INC COM 48576A100 23199 177091 SH DFND 0 177091 0 KINNATE BIOPHARMA INC COM 49705R105 4683 264293 SH DFND 0 264293 0 LILLY ELI & CO COM 532457108 82491 298643 SH DFND 0 298643 0 MCKESSON CORP COM 58155Q103 43997 177000 SH DFND 0 177000 0 MIRATI THERAPEUTICS INC COM 60468T105 46273 315449 SH DFND 0 315449 0 MOLINA HEALTHCARE INC COM 60855R100 22294 70088 SH DFND 0 70088 0 MYRIAD GENETICS INC COM 62855J104 55909 2025681 SH DFND 0 2025681 0 NEUROCRINE BIOSCIENCES INC COM 64125C109 33562 394058 SH DFND 0 394058 0 NEVRO CORP COM 64157F103 39330 485135 SH DFND 0 485135 0 NOVAVAX INC COM NEW 670002401 12685 88663 SH DFND 0 88663 0 OAK STR HEALTH INC COM 67181A107 9258 279357 SH DFND 0 279357 0 OUTSET MED INC COM 690145107 135516 2940255 SH DFND 0 2940255 0 PARDES BIOSCIENCES INC COM 69945Q105 5918 361528 SH DFND 0 361528 0 PENUMBRA INC COM 70975L107 50881 177088 SH DFND 0 177088 0 PFIZER INC COM 717081103 79327 1343384 SH DFND 0 1343384 0 PMV PHARMACEUTICALS INC COM 69353Y103 6661 288334 SH DFND 0 288334 0 PRAXIS PRECISION MEDICINES I COM 74006W108 12527 635904 SH DFND 0 635904 0 PROCEPT BIOROBOTICS CORP COM 74276L105 1626 65000 SH DFND 0 65000 0 PULMONX CORP COM 745848101 6709 209193 SH DFND 0 209193 0 SEAGEN INC COM 81181C104 41514 268527 SH DFND 0 268527 0 SOPHIA GENETICS SA ORDINARY SHARES H82027105 27525 1952152 SH DFND 0 1952152 0 SPDR SER TR CALL 78464A900 27553 246100 SH Call DFND 0 246100 0 SYNDAX PHARMACEUTICALS INC COM 87164F105 46046 2103512 SH DFND 0 2103512 0 TENET HEALTHCARE CORP COM NEW 88033G407 42963 525927 SH DFND 0 525927 0 THERMO FISHER SCIENTIFIC INC COM 883556102 41464 62143 SH DFND 0 62143 0 UNITEDHEALTH GROUP INC COM 91324P102 56016 111554 SH DFND 0 111554 0 UNIVERSAL HLTH SVCS INC CL B 913903100 61633 475340 SH DFND 0 475340 0 WATERS CORP COM 941848103 43830 117634 SH DFND 0 117634 0 WEREWOLF THERAPEUTICS INC COM 95075A107 4764 400000 SH DFND 0 400000 0