ABBVIE INC COM 00287Y109 1082 17474 SH DFND 0 17474 0 ABBVIE INC COM 00287Y109 256 4546 SH DFND 0 4546 0 ABBVIE INC COM 00287Y109 101 1794 SH DFND 0 1794 0 ACCURAY INC COM 004397105 377 72684 SH DFND 0 72684 0 AERIE PHARMACEUTICALS INC COM 00771V108 780 44345 SH DFND 0 44345 0 AETNA INC NEW COM 00817Y108 2277 18640 SH DFND 0 18640 0 ALDER BIOPHARMACEUTICALS INC COM 014339105 1873 75002 SH DFND 0 75002 0 ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 444 5585 SH DFND 0 5585 0 AMAZON COM INC COM 023135106 1083 1514 SH DFND 0 1514 0 ANTERO RES CORP COM 03674X106 770 29620 SH DFND 0 29620 0 APPLE INC COM 037833100 211 2207 SH DFND 0 2207 0 APPLIED MATLS INC CALL 038222905 976 40700 SH Call DFND 0 40700 0 APPLIED MATLS INC COM 038222105 1529 63793 SH DFND 0 63793 0 BAXTER INTL INC COM 071813109 1257 27804 SH DFND 0 27804 0 BECTON DICKINSON & CO COM 075887109 835 4924 SH DFND 0 4924 0 BIOGEN INC COM 09062X103 1726 7139 SH DFND 0 7139 0 BIOMARIN PHARMACEUTICAL INC COM 09061G101 914 11752 SH DFND 0 11752 0 BLUEPRINT MEDICINES CORP COM 09627Y109 406 20049 SH DFND 0 20049 0 BRISTOL MYERS SQUIBB CO CALL 110122908 2398 32600 SH Call DFND 0 32600 0 BRISTOL MYERS SQUIBB CO COM 110122108 669 9099 SH DFND 0 9099 0 BROOKDALE SR LIVING INC COM 112463104 1046 67761 SH DFND 0 67761 0 CBRE GROUP INC CL A 12504L109 788 29774 SH DFND 0 29774 0 CIRRUS LOGIC INC COM 172755100 895 23076 SH DFND 0 23076 0 CLOVIS ONCOLOGY INC COM 189464100 431 31406 SH DFND 0 31406 0 CLOVIS ONCOLOGY INC NOTE 2.500% 9/1 189464AB6 1082 1520000 PRN DFND 0 1520000 0 COMMSCOPE HLDG CO INC COM 20337X109 821 26464 SH DFND 0 26464 0 DEVON ENERGY CORP NEW COM 25179M103 462 12741 SH DFND 0 12741 0 DIMENSION THERAPEUTICS INC COM 25433V105 89 14761 SH DFND 0 14761 0 DISH NETWORK CORP CL A 25470M109 1061 20246 SH DFND 0 20246 0 EDWARDS LIFESCIENCES CORP COM 28176E108 2262 22683 SH DFND 0 22683 0 ENDOLOGIX INC COM 29266S106 396 31800 SH DFND 0 31800 0 FACEBOOK INC CL A 30303M102 1554 13595 SH DFND 0 13595 0 GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 338 20383 SH DFND 0 20383 0 GW PHARMACEUTICALS PLC PUT 36197T953 302 3300 SH Put DFND 0 3300 0 HALLIBURTON CO COM 406216101 683 15080 SH DFND 0 15080 0 HCA HOLDINGS INC COM 40412C101 1046 13578 SH DFND 0 13578 0 HERBALIFE LTD NOTE 2.000% 8/1 42703MAB9 1049 1058000 PRN DFND 0 1058000 0 HERBALIFE LTD COM USD SHS G4412G101 765 13069 SH DFND 0 13069 0 HERON THERAPEUTICS INC COM 427746102 871 48279 SH DFND 0 48279 0 HOLOGIC INC COM 436440101 651 18827 SH DFND 0 18827 0 HORTONWORKS INC COM 440894103 212 19799 SH DFND 0 19799 0 INNOVIVA INC COM 45781M101 28 2703 SH DFND 0 2703 0 INSYS THERAPEUTICS INC NEW PUT 45824V959 14 1100 SH Put DFND 0 1100 0 ISHARES TR PUT 464287956 489 1900 SH Put DFND 0 1900 0 JAZZ PHARMACEUTICALS PLC CALL G50871905 579 4100 SH Call DFND 0 4100 0 JAZZ PHARMACEUTICALS PLC SHS USD G50871105 1443 10209 SH DFND 0 10209 0 KITE PHARMA INC COM 49803L109 253 5060 SH DFND 0 5060 0 KURA ONCOLOGY INC COM 50127T109 62 23023 SH DFND 0 23023 0 LILLY ELI & CO PUT 532457958 630 8000 SH Put DFND 0 8000 0 LILLY ELI & CO PUT 532457958 969 12300 SH Put DFND 0 12300 0 LIVANOVA PLC SHS G5509L101 251 4993 SH DFND 0 4993 0 MCKESSON CORP COM 58155Q103 1107 5929 SH DFND 0 5929 0 MEDICINES CO COM 584688105 1709 50808 SH DFND 0 50808 0 MEDICINES CO NOTE 2.500% 1/1 584688AE5 164 139000 PRN DFND 0 139000 0 MERCK & CO INC PUT 58933Y955 2500 43400 SH Put DFND 0 43400 0 MICROSOFT CORP COM 594918104 887 17341 SH DFND 0 17341 0 MOLINA HEALTHCARE INC COM 60855R100 322 6445 SH DFND 0 6445 0 MYOKARDIA INC COM 62857M105 201 16187 SH DFND 0 16187 0 OREXIGEN THERAPEUTICS INC NOTE 2.750%12/0 686164AB0 145 403000 PRN DFND 0 403000 0 PALO ALTO NETWORKS INC COM 697435105 666 5427 SH DFND 0 5427 0 POWERSHARES QQQ TRUST CALL 73935A904 1075 10000 SH Call DFND 0 10000 0 PUMA BIOTECHNOLOGY INC COM 74587V107 677 22740 SH DFND 0 22740 0 REGENERON PHARMACEUTICALS PUT 75886F957 664 1900 SH Put DFND 0 1900 0 RICE ENERGY INC COM 762760106 322 14613 SH DFND 0 14613 0 SELECT SECTOR SPDR TR CALL 81369Y906 976 14300 SH Call DFND 0 14300 0 SELECT SECTOR SPDR TR PUT 81369Y959 1327 18500 SH Put DFND 0 18500 0 SPECTRANETICS CORP COM 84760C107 108 5780 SH DFND 0 5780 0 TENET HEALTHCARE CORP COM NEW 88033G407 363 13136 SH DFND 0 13136 0 U S SILICA HLDGS INC COM 90346E103 223 6456 SH DFND 0 6456 0 UNITEDHEALTH GROUP INC COM 91324P102 1094 7747 SH DFND 0 7747 0 UNIVERSAL HLTH SVCS INC CL B 913903100 685 5105 SH DFND 0 5105 0 VERTEX PHARMACEUTICALS INC COM 92532F100 295 3425 SH DFND 0 3425 0 VIPSHOP HLDGS LTD SPONSORED ADR 92763W103 275 24662 SH DFND 0 24662 0 VIPSHOP HLDGS LTD NOTE 1.500% 3/1 92763WAA1 1098 1112000 PRN DFND 0 1112000 0 VISA INC COM CL A 92826C839 295 3982 SH DFND 0 3982 0 VOYAGER THERAPEUTICS INC COM 92915B106 288 26187 SH DFND 0 26187 0 VULCAN MATLS CO COM 929160109 357 2964 SH DFND 0 2964 0 WALGREENS BOOTS ALLIANCE INC COM 931427108 1476 17725 SH DFND 0 17725 0 ZELTIQ AESTHETICS INC COM 98933Q108 347 12713 SH DFND 0 12713 0