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Stockholders' Equity - Summary of Stock Option Activity (Detail)
9 Months Ended
Sep. 30, 2016
$ / shares
shares
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]  
Outstanding Beginning Balance, Number of Shares | shares 742,997
Granted, Number of Shares | shares 705,125
Canceled/Forfeited, Number of Shares | shares (176,264)
Outstanding Ending Balance, Number of Shares | shares 1,271,858
Outstanding Beginning Balance, Weighted-Average Exercise Price Per Share $ 16.32
Granted, Weighted-Average Exercise Price Per Share 4.00
Canceled/Forfeited, Weighted Average Exercise Price Per Share 13.15
Outstanding Ending Balance, Weighted Average Exercise Price Per Share 9.46
Outstanding, 6.24-30.00 [Member]  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]  
Exercise Price Per Share, Minimum 6.24
Exercise Price Per Share, Maximum 30.00
Granted, 3.12-6.40 [Member]  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]  
Exercise Price Per Share, Minimum 2.15
Exercise Price Per Share, Maximum 6.40
Canceled/Forfeited, 6.24-30.00 [Member]  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]  
Exercise Price Per Share, Minimum 6.24
Exercise Price Per Share, Maximum 30.00
Outstanding, 3.12-30.00 [Member]  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]  
Exercise Price Per Share, Minimum 2.15
Exercise Price Per Share, Maximum $ 30.00