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CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($)
Total
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Deficit[Member]
Beginning Balance at Dec. 31, 2013 $ 53,980,890 $ 95,815 $ 119,410,777 $ (65,525,702)
Beginning Balance, Shares at Dec. 31, 2013   95,814,565    
Stock-based compensation 1,637,022   1,637,022  
Sale of common stock and warrants, net of issuance costs, Value $ 18,577,018 $ 10,192 18,566,826  
Sale of common stock and warrants, net of issuance costs, Shares 15,786,739 10,192,500    
Note and accrued interest conversions, Value $ 11,130,261 $ 5,574 11,124,687  
Note and accrued interest conversions, Shares 5,573,831 5,573,831    
Common stock issued for services, Value $ 50,000 $ 20 49,980  
Common stock issued for services, Shares 20,408 20,408    
Net loss $ (9,897,678)     (9,897,678)
Ending Balance at Dec. 31, 2014 75,477,513 $ 111,601 150,789,292 (75,423,380)
Ending Balance, Shares at Dec. 31, 2014   111,601,304    
Stock-based compensation $ 1,350,387   1,350,387  
Sale of common stock and warrants, net of issuance costs, Shares 186,921      
Shares issued for vested restricted stock units, Value   $ 57 (57)  
Shares issued for vested restricted stock units, Shares 56,500 56,500    
Shares issued for Employee Stock Purchase Plan options, Value $ 110,066 $ 130 109,936  
Shares issued for Employee Stock Purchase Plan options, Shares 130,421 130,421    
Net loss $ (7,445,930)     (7,445,930)
Ending Balance at Dec. 31, 2015 $ 69,492,036 $ 111,788 $ 152,249,558 $ (82,869,310)
Ending Balance, Shares at Dec. 31, 2015   111,788,225