Income Taxes - Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Deferred tax assets:
Net operating losses	$ 114,153	$ 107,170
Tax credits	39,002	34,885
Deferred revenue	310	521
Equity compensation	5,024	3,994
Lease liabilities	16,138	17,465
Accrued compensation	5,864	3,225
Bad debt	598	502
Other accrued expense	663	318
Capitalized research and development costs	36,186	45,820
Other	3,855	4,033
Gross deferred tax assets	221,793	217,933
Less: Valuation allowance	(191,198)	(187,969)
Total deferred tax assets	30,595	29,964
Deferred tax liabilities:
Prepaid expenses	(11,518)	(13,298)
Right-of-use assets	(7,809)	(8,406)
Depreciation	(2,363)	(3,245)
Intangible assets	(380)	(688)
Other	(3,675)	(198)
Total deferred tax liabilities	(25,745)	(25,835)
Net deferred tax assets	$ 4,850	$ 4,129