ABEONA THERAPEUTICS INC COM NEW 00289Y206 1054000 200000 SH Call SOLE 200000 0 0 ABEONA THERAPEUTICS INC COM NEW 00289Y206 3739091 709505 SH SOLE 709505 0 0 ACADIA PHARMACEUTICALS INC COM 004225108 2671000 100000 SH SOLE 100000 0 0 ADICET BIO INC COM NEW 007002207 1852493 220011 SH SOLE 220011 0 0 ADMA BIOLOGICS INC COM 000899104 13497600 740000 SH SOLE 740000 0 0 ALEXANDRIA REAL ESTATE EQ IN COM NEW 015271109 2447000 50000 SH Call SOLE 50000 0 0 AN2 THERAPEUTICS INC COM 037326105 715542 627668 SH SOLE 627668 0 0 AYTU BIOPHARMA INC COM 054754858 2115630 813704 SH SOLE 813704 0 0 BIOAGE LABS INC COM 09077V100 595350 45000 SH SOLE 45000 0 0 BOUNDLESS BIO INC COM 10170A100 852085 710071 SH SOLE 710071 0 0 CABALETTA BIO INC COM 12674W109 374709 171100 SH SOLE 171100 0 0 CAMP4 THERAPEUTICS CORP COM 13463J101 1403120 228894 SH SOLE 228894 0 0 CNS PHARMACEUTICALS INC COM 18978H508 256342 48827 SH SOLE 48827 0 0 CODEXIS INC COM 192005106 417453 256106 SH SOLE 256106 0 0 COMPUGEN LTD ORD M25722105 467262 305400 SH SOLE 305400 0 0 CORBUS PHARMACEUTICALS HLDGS COM NEW 21833P301 3173916 389916 SH SOLE 389916 0 0 CRESCENT BIOPHARMA INC. COM G2545C104 1039909 87682 SH SOLE 87682 0 0 CRISPR THERAPEUTICS AG NAMEN AKT H17182108 2622000 50000 SH Call SOLE 50000 0 0 CURIS INC COM 231269309 58583 59349 SH SOLE 59349 0 0 CYBIN INC COM NEW 23256X407 2780398 339902 SH SOLE 339902 0 0 DAY ONE BIOPHARMACEUTICALS I COM 23954D109 1864000 200000 SH SOLE 200000 0 0 DELCATH SYS INC COM NEW 24661P807 275043 27232 SH SOLE 27232 0 0 EDESA BIOTECH INC COM NEW 27966L306 976250 687500 SH SOLE 687500 0 0 ELEDON PHARMACEUTICALS INC COM 28617K101 1348581 893100 SH SOLE 893100 0 0 ENANTA PHARMACEUTICALS INC COM 29251M106 1577000 100000 SH SOLE 100000 0 0 EVAXION AS SPONSORED ADS 29970R303 95400 20000 SH SOLE 20000 0 0 EVOLUS INC COM 30052C107 10850060 1631588 SH SOLE 1631588 0 0 FENNEC PHARMACEUTICALS INC COM 31447P100 385000 50000 SH SOLE 50000 0 0 GERON CORP COM 374163103 1063656 805800 SH SOLE 805800 0 0 GOSSAMER BIO INC COM 38341P102 634787 204770 SH SOLE 204770 0 0 HERON THERAPEUTICS INC COM 427746102 1609143 1237802 SH SOLE 1237802 0 0 IN8BIO INC COM NEW 45674E208 385850 164893 SH SOLE 164893 0 0 INDIVIOR PLC ORD G4766E116 3588000 100000 SH SOLE 100000 0 0 INHIBIKASE THERAPEUTICS INC COM NEW 45719W205 4813701 2348147 SH SOLE 2348147 0 0 JANUX THERAPEUTICS INC COM 47103J105 276000 20000 SH SOLE 20000 0 0 KAZIA THERAPEUTICS LTD SPONSORED ADS 48669G303 3171874 460359 SH SOLE 460359 0 0 KEZAR LIFE SCIENCES INC COM NEW 49372L209 982366 156179 SH SOLE 156179 0 0 KIORA PHARMACEUTICALS INC COM 49721T507 258354 131144 SH SOLE 131144 0 0 MANNKIND CORP COM NEW 56400P706 489656 86359 SH SOLE 86359 0 0 MAXCYTE INC COM 57777K106 726978 469018 SH SOLE 469018 0 0 MILESTONE PHARMACEUTICALS IN COM 59935V107 1338585 662666 SH SOLE 662666 0 0 NEKTAR THERAPEUTICS COM NEW 640268306 2114000 50000 SH Call SOLE 50000 0 0 NEKTAR THERAPEUTICS COM NEW 640268306 3593800 85000 SH SOLE 85000 0 0 OMNIAB INC COM 68218J103 1296850 701000 SH SOLE 701000 0 0 OVID THERAPEUTICS INC COM 690469101 166858 102367 SH SOLE 102367 0 0 PASITHEA THERAPEUTICS CORP COM NEW 70261F202 354830 275062 SH SOLE 275062 0 0 PLIANT THERAPEUTICS INC COM 729139105 280661 230050 SH SOLE 230050 0 0 PMV PHARMACEUTICALS INC COM 69353Y103 1438449 1150759 SH SOLE 1150759 0 0 PROCESSA PHARMACEUTICALS INC COM SHS 74275C403 35490 12323 SH SOLE 12323 0 0 PULMONX CORP COM 745848101 1074944 486400 SH SOLE 486400 0 0 QUOIN PHARMACEUTICALS LTD SPONSORED ADS 74907L409 1128267 78189 SH SOLE 78189 0 0 RADIOPHARM THERANOSTICS LTD SPONSORED ADS 75041J101 850851 51000000 SH SOLE 51000000 0 0 SEMLER SCIENTIFIC INC COM 81684M104 764500 50000 SH SOLE 50000 0 0 SPRUCE BIOSCIENCES INC COM NEW 85209E208 1719726 19742 SH SOLE 19742 0 0 SURROZEN INC COM NEW 86889P208 2568061 113631 SH SOLE 113631 0 0 TELA BIO INC COM 872381108 2775398 2352032 SH SOLE 2352032 0 0 TENAX THERAPEUTICS INC COM NEW 88032L605 144866 11884 SH SOLE 11884 0 0 TENAYA THERAPEUTICS INC COM 87990A106 250449 352001 SH SOLE 352001 0 0 ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 2300000 100000 SH Call SOLE 100000 0 0 VERASTEM INC COM NEW 92337C203 21091650 2732079 SH SOLE 2732079 0 0 VERRICA PHARMACEUTICALS INC COM SHS 92511W207 2938989 353669 SH SOLE 353669 0 0 X4 PHARMACEUTICALS INC COM NEW 98420X202 2374292 593573 SH SOLE 593573 0 0 XILIO THERAPEUTICS INC COM 98422T100 80838 126270 SH SOLE 126270 0 0 XOMA ROYALTY CORPORATION COM NEW 98419J206 3057850 115000 SH SOLE 115000 0 0 ZENTALIS PHARMACEUTICALS INC COM 98943L107 625995 463700 SH SOLE 463700 0 0 ZEVRA THERAPEUTICS INC COM NEW 488445206 5099028 569088 SH SOLE 569088 0 0