<?xml version="1.0" encoding="UTF-8"?><!-- Generated by CompSci Transform (tm) - http://www.compsciresources.com --><!-- Created: Mon Feb 23 21:27:40 UTC 2026 --><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:common="http://www.sec.gov/edgar/common" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001697361</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>


    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001439725</issuerCik>
      <issuerName>BIODESIX INC</issuerName>
      <secFileNumber>001-39659</secFileNumber>
      <issuerAddress>
        <common:street1>919 WEST DILLON RD</common:street1>
        <common:city>LOUISVILLE</common:city>
        <common:stateOrCountry>CO</common:stateOrCountry>
        <common:zipCode>80027</common:zipCode>
      </issuerAddress>
      <issuerContactPhone>303-417-0500</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Hutton Scott</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
        <relationshipToIssuer>Director</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Morgan Stanley Smith Barney LLC</name>
        <address>
          <common:street1>1 New York Plaza</common:street1>
          <common:street2>38th Floor</common:street2>
          <common:city>New York</common:city>
          <common:stateOrCountry>NY</common:stateOrCountry>
          <common:zipCode>10004</common:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>1490</noOfUnitsSold>
      <aggregateMarketValue>19027.3</aggregateMarketValue>
      <noOfUnitsOutstanding>7955685</noOfUnitsOutstanding>
      <approxSaleDate>02/23/2026</approxSaleDate>
      <securitiesExchangeName>NASDAQ</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <acquiredDate>02/20/2026</acquiredDate>
      <natureOfAcquisitionTransaction>Settlement of vested RSUs issued under an S-8 Registered Plan</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>4844</amountOfSecuritiesAcquired>
      <paymentDate>02/20/2026</paymentDate>
      <natureOfPayment>Equity compensation for services rendered</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Scott Hutton</name>
        <address>
          <common:street1>919 WEST DILLON RD</common:street1>
          <common:city>LOUISVILLE</common:city>
          <common:stateOrCountry>CO</common:stateOrCountry>
          <common:zipCode>80027</common:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <saleDate>02/10/2026</saleDate>
      <amountOfSecuritiesSold>3559</amountOfSecuritiesSold>
      <grossProceeds>35889.31</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Scott Hutton</name>
        <address>
          <common:street1>919 WEST DILLON RD</common:street1>
          <common:city>LOUISVILLE</common:city>
          <common:stateOrCountry>CO</common:stateOrCountry>
          <common:zipCode>80027</common:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <saleDate>01/16/2026</saleDate>
      <amountOfSecuritiesSold>970</amountOfSecuritiesSold>
      <grossProceeds>7904.82</grossProceeds>
    </securitiesSoldInPast3Months>
    <remarks>Shares sold automatically to cover taxes upon the vesting of RSUs</remarks>
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    <noticeSignature>
      <noticeDate>02/23/2026</noticeDate>
      <signature>/s/ Scott Hutton</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
