Condensed Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-In Capital	Accumulated Other Comprehensive Loss	Accumulated Deficit	Treasury Stock
Beginning balance (in shares) at Dec. 31, 2022		71,256,118,000
Beginning balance at Dec. 31, 2022	$ 1,100,814	$ 71	$ 2,386,325	$ (12,535)	$ (470,561)	$ (802,486)
Treasury stock, beginning balance (in shares) at Dec. 31, 2022						(16,216,411,000)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Unrealized gain (loss) on available-for-sale securities	4,124			4,124
Common stock issued under stock incentive plan and ESPP (in shares)		501,660,000
Common stock issued under stock incentive plan and ESPP	2,467	$ 1	2,466
Stock-based compensation expense	10,139		10,139
Net loss	(81,018)				(81,018)
Ending balance (in shares) at Mar. 31, 2023		71,757,778,000
Ending balance at Mar. 31, 2023	1,036,526	$ 72	2,398,930	(8,411)	(551,579)	$ (802,486)
Treasury stock, ending balance (in shares) at Mar. 31, 2023						(16,216,411,000)
Beginning balance (in shares) at Dec. 31, 2022		71,256,118,000
Beginning balance at Dec. 31, 2022	1,100,814	$ 71	2,386,325	(12,535)	(470,561)	$ (802,486)
Treasury stock, beginning balance (in shares) at Dec. 31, 2022						(16,216,411,000)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(164,824)
Ending balance (in shares) at Jun. 30, 2023		71,951,186,000
Ending balance at Jun. 30, 2023	964,236	$ 72	2,410,905	(8,870)	(635,385)	$ (802,486)
Treasury stock, ending balance (in shares) at Jun. 30, 2023						(16,216,411,000)
Beginning balance (in shares) at Mar. 31, 2023		71,757,778,000
Beginning balance at Mar. 31, 2023	1,036,526	$ 72	2,398,930	(8,411)	(551,579)	$ (802,486)
Treasury stock, beginning balance (in shares) at Mar. 31, 2023						(16,216,411,000)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Unrealized gain (loss) on available-for-sale securities	(459)			(459)
Common stock issued under stock incentive plan and ESPP (in shares)		193,408,000
Common stock issued under stock incentive plan and ESPP	238		238
Stock-based compensation expense	11,737		11,737
Net loss	(83,806)				(83,806)
Ending balance (in shares) at Jun. 30, 2023		71,951,186,000
Ending balance at Jun. 30, 2023	$ 964,236	$ 72	2,410,905	(8,870)	(635,385)	$ (802,486)
Treasury stock, ending balance (in shares) at Jun. 30, 2023						(16,216,411,000)
Beginning balance (in shares) at Dec. 31, 2023	55,945,078	72,161,489,000
Beginning balance at Dec. 31, 2023	$ 811,019	$ 72	2,436,523	(441)	(822,649)	$ (802,486)
Treasury stock, beginning balance (in shares) at Dec. 31, 2023	(16,216,411)					(16,216,411,000)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Unrealized gain (loss) on available-for-sale securities	$ (646)			(646)
Common stock issued under stock incentive plan and ESPP (in shares)		806,433,000
Common stock issued under stock incentive plan and ESPP	5,864	$ 1	5,863
Stock-based compensation expense	9,234		9,234
Net loss	(81,549)				(81,549)
Ending balance (in shares) at Mar. 31, 2024		72,967,922,000
Ending balance at Mar. 31, 2024	$ 743,922	$ 73	2,451,620	(1,087)	(904,198)	$ (802,486)
Treasury stock, ending balance (in shares) at Mar. 31, 2024						(16,216,411,000)
Beginning balance (in shares) at Dec. 31, 2023	55,945,078	72,161,489,000
Beginning balance at Dec. 31, 2023	$ 811,019	$ 72	2,436,523	(441)	(822,649)	$ (802,486)
Treasury stock, beginning balance (in shares) at Dec. 31, 2023	(16,216,411)					(16,216,411,000)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Common stock issued under stock incentive plan and ESPP (in shares)	184,331
Net loss	$ (177,667)
Ending balance (in shares) at Jun. 30, 2024	56,875,079	73,091,490,000
Ending balance at Jun. 30, 2024	$ 660,510	$ 73	2,464,284	(1,045)	(1,000,316)	$ (802,486)
Treasury stock, ending balance (in shares) at Jun. 30, 2024	(16,216,411)					(16,216,411,000)
Beginning balance (in shares) at Mar. 31, 2024		72,967,922,000
Beginning balance at Mar. 31, 2024	$ 743,922	$ 73	2,451,620	(1,087)	(904,198)	$ (802,486)
Treasury stock, beginning balance (in shares) at Mar. 31, 2024						(16,216,411,000)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Unrealized gain (loss) on available-for-sale securities	42			42
Common stock issued under stock incentive plan and ESPP (in shares)		123,568,000
Common stock issued under stock incentive plan and ESPP	1,099		1,099
Stock-based compensation expense	11,565		11,565
Net loss	$ (96,118)				(96,118)
Ending balance (in shares) at Jun. 30, 2024	56,875,079	73,091,490,000
Ending balance at Jun. 30, 2024	$ 660,510	$ 73	$ 2,464,284	$ (1,045)	$ (1,000,316)	$ (802,486)
Treasury stock, ending balance (in shares) at Jun. 30, 2024	(16,216,411)					(16,216,411,000)