Collaboration and License Agreements - Schedule of Collaboration Revenue from CStone Agreement (Details) - USD ($) $ in Thousands	3 Months Ended	9 Months Ended
Sep. 30, 2019	Sep. 30, 2018	Sep. 30, 2019	Sep. 30, 2018
Disaggregation of Revenue [Line Items]
Revenue	$ 26,024	$ 15,198	$ 82,472	$ 64,374
License and other services
Disaggregation of Revenue [Line Items]
Revenue	0	0	0	15,000
License and other services \| CStone Agreement
Disaggregation of Revenue [Line Items]
Revenue	(103)	0	(103)	12,440
Other Services \| CStone Agreement
Disaggregation of Revenue [Line Items]
Revenue	523	0	2,305	0
Collaboration revenue – other
Disaggregation of Revenue [Line Items]
Revenue	420	0	2,202	12,440
Collaboration revenue – other \| CStone Agreement
Disaggregation of Revenue [Line Items]
Revenue	$ 420	$ 0	$ 2,202	$ 12,440

Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
-SubTopic 10
-Section 50
-Paragraph 4
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=118956577&loc=SL49130543-203045

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
-SubTopic 10
-Section 50
-Paragraph 5
-URI http://asc.fasb.org/extlink&oid=118956577&loc=SL49130545-203045

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Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration