Collaboration and License Agreements - Additional Information (Details) - USD ($)	3 Months Ended			9 Months Ended
	Sep. 30, 2019	Sep. 30, 2018	Jun. 30, 2018	Sep. 30, 2019	Sep. 30, 2018
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Remaining unsatisfied performance obligation	$ 70,800,000			$ 70,800,000
Milestones achieved	0	$ 0		0	$ 0
2010 Agreement
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Potential milestone payment	$ 35,000,000.0			$ 35,000,000.0
Collaboration revenue – related party
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Milestones achieved			$ 15,000,000.0