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We hereby consent to the incorporation by reference in the Registration Statements on Form S-8 (Nos. 333-223031, 333-216106, 333-209755, 333-201796, 333- 193802, and 333-190101) and Form S-3 (No. 333-221960) of Agios Pharmaceuticals, Inc. of our report dated February 14, 2019 relating to the financial statements and the effectiveness of internal control over financial reporting, which appears in this Form 10-K.